Isobutanol

Isobutanol

SCHEMBL4243770

CC(C)CO.COCCO

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.53
PIK3CD O00329 1/20 0.37
TDP1 Q9NUW8 1/20 0.35
MAPK1 P28482 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ROCK2 O75116 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propylene Glycol SCHEMBL17967765 0.86 TDP1 (0.56) TSHRPIK3CDTDP1MAPK1ALDH1A1
2-Methoxyethanol SCHEMBL8858436 0.85
2-Methoxyethanol SCHEMBL310 0.84
2-Methoxyethanol SCHEMBL1317307 0.84 TSHR (0.47) TSHRMAPK1ALDH1A1MEN1KMT2A
Propylene Glycol SCHEMBL7219184 0.81 TDP1 (0.50) TSHRTDP1MAPK1ALDH1A1
1,3-Butanediol SCHEMBL10457134 0.81 TDP1 (0.36) TSHRTDP1MAPK1ALDH1A1ROCK2
2-Methoxyethanol SCHEMBL6014126 0.81
2-Methoxyethanol SCHEMBL4455759 0.81
2-Methoxyethanol SCHEMBL8506499 0.81
2-Methoxyethanol SCHEMBL3886889 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090004482-A1 Method of making a stabilized colloidal silica, compositions comprising the same, and coated articles including the same GUARDIAN INDUSTRIES CORP. (US) 2009-01-01 US disclosed
WO-2009002377-A1 METHOD OF MAKING A STABILIZED COLLOIDAL SILICA, COMPOSITIONS COMPRISING THE SAME, AND COATED ARTICLES INCLUDING THE SAME GUARDIAN INDUSTRIES CORP. (US) 2008-12-31 WO disclosed