Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4244338 | 1.00 | CCR5 (0.80) | CCR5KCNH2 | |
| SCHEMBL4237895 | 0.91 | CCR5 (0.66) | CCR5KCNH2 | |
| SCHEMBL4237890 | 0.91 | CCR5 (0.66) | CCR5KCNH2 | |
| SCHEMBL4241579 | 0.91 | CCR5 (0.78) | CCR5KCNH2 | |
| SCHEMBL4241576 | 0.91 | CCR5 (0.78) | CCR5KCNH2 | |
| SCHEMBL13920735 | 0.90 | CCR5 (0.67) | CCR5KCNH2 | |
| SCHEMBL4241609 | 0.90 | CCR5 (0.77) | CCR5KCNH2 | |
| SCHEMBL4241606 | 0.90 | CCR5 (0.77) | CCR5KCNH2 | |
| SCHEMBL4246998 | 0.90 | CCR5 (0.87) | CCR5KCNH2 | |
| SCHEMBL4247005 | 0.90 | CCR5 (0.87) | CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498346-B2 | viricide, antiinflammatory agent; autoimmune diseases; protective effects against infection of target cells by a human immunodeficiency virus (HIV); 6-Chloro-N-((R)-3-{4-[(4-methoxy-phenyl)-(4-methyl-pyridin-3-ylmethyl)-amino]-piperidin-1-yl}-butyl)-2,4-dimethyl-nicotinamide | GENZYME CORPORATION (US) | 2009-03-03 | — | — | US | disclosed |