Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4244862 | 1.00 | KIF11 (0.53) | KIF11 | |
| SCHEMBL4244615 | 0.93 | KIF11 (0.54) | KIF11 | |
| SCHEMBL4244618 | 0.93 | KIF11 (0.54) | KIF11 | |
| SCHEMBL4255892 | 0.93 | KIF11 (0.55) | KIF11 | |
| SCHEMBL4244627 | 0.93 | KIF11 (0.60) | KIF11 | |
| SCHEMBL4255886 | 0.93 | KIF11 (0.55) | KIF11 | |
| SCHEMBL4244624 | 0.93 | KIF11 (0.60) | KIF11 | |
| SCHEMBL4252111 | 0.93 | KIF11 (0.53) | KIF11 | |
| SCHEMBL4252114 | 0.93 | KIF11 (0.53) | KIF11 | |
| SCHEMBL4248818 | 0.92 | KIF11 (0.54) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035426-A1 | PYRAZOLOPYRIMIDONES | 4SC AG (DE) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007144384-A1 | PYRAZOLOPYRIMIDONES | 4SC AG (DE) | 2007-12-21 | — | — | WO | disclosed |