Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 13/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.61 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13878559 | 0.94 | CHRNA7 (0.65) | CHRNA7KCNH2GPR35ALDH1A1HPGD | |
| Trifluoroacetic Acid SCHEMBL4243437 | 0.91 | CHRNA7 (0.65) | CHRNA7KCNH2ALDH1A1NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL4238449 | 0.89 | CHRNA7 (0.63) | CHRNA7KCNH2ALDH1A1HPGDNPC1 | |
| Trifluoroacetic Acid SCHEMBL4239253 | 0.85 | CHRNA7 (0.46) | CHRNA7KCNH2ALDH1A1HPGDHSD17B10 | |
| Trifluoroacetic Acid SCHEMBL4244808 | 0.84 | CHRNA7 (0.61) | CHRNA7KCNH2MAPK1 | |
| SCHEMBL13878633 | 0.84 | CHRNA7 (0.69) | CHRNA7KCNH2ALDH1A1NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL4243421 | 0.83 | CHRNA7 (0.67) | CHRNA7KCNH2KDM4ESMN1; SMN2MEN1 | |
| Trifluoroacetic Acid SCHEMBL4247316 | 0.83 | CHRNA7 (0.59) | CHRNA7KCNH2HPGDKDM4E | |
| Trifluoroacetic Acid SCHEMBL4243478 | 0.83 | CHRNA7 (0.61) | CHRNA7KCNH2HPGDRAB9AHSD17B10 | |
| SCHEMBL13878556 | 0.82 | CHRNA7 (0.67) | CHRNA7KCNH2ALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105217-A1 | 2-PHENYL-5-AMINO-1,3,4-OXADIAZOLES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105217-A1 | 2-PHENYL-5-AMINO-1,3,4-OXADIAZOLES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | CHRNA7, CHRNA5, CHRNA2 | CHRNA7 1/4885KCNH2 815/4885GPR35 67/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.