Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.65 |
| ▸ | STAT3 | P40763 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | NR2F2 | P24468 | 4/20 | 0.60 |
| ▸ | HRH1 | P35367 | 1/20 | 0.58 |
| ▸ | AKT2 | P31751 | 2/20 | 0.56 |
| ▸ | KIT | P10721 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PEAK1 | Q9H792 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30945075 | 1.00 | HTR2C (0.65) | HTR2CSTAT3MAPTHTTSMN1; SMN2 | |
| SCHEMBL17516462 | 0.85 | HTR2C (0.65) | HTR2CSTAT3MAPTHTTSMN1; SMN2 | |
| SCHEMBL4192433 | 0.85 | HTR2C (0.65) | HTR2CSTAT3MAPTHTTSMN1; SMN2 | |
| SCHEMBL5107750 | 0.80 | HTR2C (0.70) | HTR2CSTAT3MAPTHTTSMN1; SMN2 | |
| SCHEMBL12789895 | 0.80 | MEN1 (0.71) | HTR2CSTAT3MAPTHTTSMN1; SMN2 | |
| SCHEMBL29230284 | 0.79 | STAT3 (0.61) | HTR2CSTAT3MAPTHTTSMN1; SMN2 | |
| SCHEMBL4922800 | 0.79 | HTR2C (1.00) | HTR2CSTAT3MAPTHTTSMN1; SMN2 | |
| SCHEMBL1900780 | 0.79 | STAT3 (1.00) | HTR2CSTAT3MAPTHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30569569 | 0.78 | HTR2C (0.97) | HTR2CSTAT3MAPTHTTSMN1; SMN2 | |
| SCHEMBL4440479 | 0.77 | L3MBTL1 (0.72) | HTR2CSTAT3MAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118146226-A | Pyrrolo [2,3-d ] pyrimidine compound with nitrogen-containing heterocyclic structure, and preparation method and application thereof | 贵州大学 | 2024-06-07 | — | — | CN | disclosed |
| US-20090124610-A1 | PHARMACEUTICAL COMPOUNDS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-05-14 | — | — | US | disclosed |
| US-20090124610-A1 | PHARMACEUTICAL COMPOUNDS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-05-14 | — | — | US | disclosed |
| US-20090124610-A1 | PHARMACEUTICAL COMPOUNDS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-05-14 | — | — | US | disclosed |
| US-20040138238-A1 | Substituted aminopyrimidine compounds as neurokinin antagonists | PREDIX PHARMACEUTICALS HOLDINGS, INC. | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124610-A1 | PHARMACEUTICAL COMPOUNDS | GRK3, GRK4, CDK1 | HTR2C 686/4885STAT3 361/4885MAPT 1230/4885 |
| US-20040138238-A1 | Substituted aminopyrimidine compounds as neurokinin antagonists | TACR1, GRPR, BDKRB1 | HTR2C 223/4885STAT3 861/4885MAPT 1853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.