Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.55 |
| ▸ | CA1 | P00915 | 6/20 | 0.50 |
| ▸ | CA2 | P00918 | 6/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3358808 | 0.90 | PTGS2 (0.55) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL4247517 | 0.88 | PTGS2 (0.51) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL4245103 | 0.87 | PTGS2 (0.60) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL3355812 | 0.87 | PTGS2 (0.52) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL4248349 | 0.86 | PTGS2 (0.75) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL4245198 | 0.85 | PTGS2 (0.57) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL3354633 | 0.84 | PTGS2 (0.80) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL3355058 | 0.84 | PTGS2 (0.55) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL3355870 | 0.84 | PTGS2 (0.55) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL5206224 | 0.82 | PTGS2 (0.60) | PTGS2PTGS1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473700-B2 | 1,2,4-triazole derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same | CJ CORPORATION (KR) | 2009-01-06 | — | — | US | claimed |
| US-20060074118-A1 | 1, 2, 4 - Triazole derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same | CJ CORPORATION (JP) | 2006-04-06 | — | — | US | claimed |
| US-7473700-B2 | 1,2,4-triazole derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same | CJ CORPORATION (KR) | 2009-01-06 | — | — | US | disclosed |
| US-7473700-B2 | 1,2,4-triazole derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same | CJ CORPORATION (KR) | 2009-01-06 | — | — | US | disclosed |
| US-7473700-B2 | 1,2,4-triazole derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same | CJ CORPORATION (KR) | 2009-01-06 | — | — | US | disclosed |
| US-20060074118-A1 | 1, 2, 4 - Triazole derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same | CJ CORPORATION (JP) | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074118-A1 | 1, 2, 4 - Triazole derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same | CYP4B1, CYP3A4, CYP3A5 | PTGS2 2356/4885PTGS1 808/4885CA1 2194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.