Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB | P07437 | 2/20 | 0.49 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.45 |
| ▸ | POLA1 | P09884 | 1/20 | 0.45 |
| ▸ | ACLY | P53396 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1320525 | 0.94 | KCNA5 (0.52) | TUBBKCNA5POLA1ACLYHDAC3 | |
| SCHEMBL13905620 | 0.93 | TUBB (0.48) | TUBBKCNA5POLA1ACLYHDAC3 | |
| SCHEMBL12119507 | 0.92 | CYP2C9 (0.50) | TUBBKCNA5POLA1ACLYHDAC3 | |
| SCHEMBL1110328 | 0.89 | NAMPT (0.55) | TUBBKCNA5NAMPTHTT | |
| SCHEMBL1110102 | 0.89 | TUBB (0.46) | TUBBKCNA5POLA1ACLYHDAC3 | |
| SCHEMBL1110231 | 0.88 | HIF1A (0.45) | TUBBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1110530 | 0.87 | TUBB (0.45) | TUBBKCNA5POLA1ACLYHDAC3 | |
| SCHEMBL12119338 | 0.86 | TUBB (0.44) | TUBBKCNA5POLA1ACLYHDAC3 | |
| SCHEMBL12119339 | 0.86 | MAPT (0.48) | KCNA5HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1110229 | 0.85 | NAMPT (0.57) | MEN1KMT2ANAMPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009127723-A1 | NEW ARYLSULPHONYLGLYCINE DERIVATIVES, THE PREPARATION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-10-22 | — | — | WO | disclosed |