Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK11 | Q15759 | 9/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 7/20 | 0.48 |
| ▸ | MAPK12 | P53778 | 6/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4241190 | 0.97 | MAPK11 (0.49) | MAPK11MAPK14MAPK13MAPK12CYP2C9 | |
| SCHEMBL4240304 | 0.93 | MAPK11 (0.48) | MAPK11MAPK14MAPK13MAPK12CYP2C9 | |
| SCHEMBL4241041 | 0.90 | MAPK11 (0.45) | MAPK11MAPK14MAPK13MAPK12CYP2C9 | |
| SCHEMBL4245202 | 0.86 | MAPK13 (0.53) | MAPK11MAPK14MAPK13MAPK12CYP2C9 | |
| SCHEMBL5806925 | 0.85 | MAPK11 (0.51) | MAPK11MAPK14MAPK13MAPK12CYP2C9 | |
| SCHEMBL4245632 | 0.83 | MAPK11 (0.51) | MAPK11MAPK14MAPK13MAPK12CYP2C9 | |
| SCHEMBL4243757 | 0.83 | MAPK11 (0.51) | MAPK11MAPK14MAPK13MAPK12CYP2C9 | |
| SCHEMBL4240297 | 0.83 | MAPK13 (0.50) | MAPK11MAPK14MAPK13MAPK12CYP2C9 | |
| SCHEMBL4240989 | 0.83 | MAPK13 (0.50) | MAPK11MAPK14MAPK13MAPK12CYP2C9 | |
| SCHEMBL4760875 | 0.82 | MAPK13 (0.49) | MAPK11MAPK14MAPK13MAPK12CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042856-A1 | PYRIDAZINONE DERIVATIVES USED FOR THE TREATMENT OF PAIN | ASTELLAS PHARMA INC (JP) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042856-A1 | PYRIDAZINONE DERIVATIVES USED FOR THE TREATMENT OF PAIN | HRH2, OPRD1, HRH4 | MAPK11 1195/4885MAPK14 852/4885MAPK13 1439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.