Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30489617 | 1.00 | KDM4E (0.39) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9351612 | 1.00 | KDM4E (0.39) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL11381584 | 0.89 | ELANE (0.32) | KDM4ELMNAELANE | |
| SCHEMBL9782401 | 0.85 | ESR1 (0.34) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL11488082 | 0.85 | ESR1 (0.34) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL13986226 | 0.79 | KDM4E (0.33) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9698851 | 0.78 | ELANE (0.34) | KDM4ELMNAESR1CHRM1ELANE | |
| SCHEMBL11128354 | 0.78 | KDM4E (0.34) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL11061309 | 0.77 | ELANE (0.52) | KMT2AELANE | |
| SCHEMBL9782425 | 0.77 | ELANE (0.52) | KMT2AELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8753875-B2 | Compositions and means for diagnosing microbial infections | STATENS SERUM INSTITUT (DK) | 2014-06-17 | — | — | US | disclosed |
| US-20090068696-A1 | COMPOSITIONS AND MEANS FOR DIAGNOSING MICROBIAL INFECTIONS | STATENS SERUM INSTITUT | 2009-03-12 | — | — | US | disclosed |
| EP-0658162-A1 | CARBAPENEM DERIVATIVES AND PROCESSES FOR PREPARING THE SAME | DONG-A PHARM. CO., LTD. (KR) | 1995-06-21 | — | — | EP | disclosed |
| WO-1994005667-A1 | CARBAPENEM DERIVATIVES AND PROCESSES FOR PREPARING THE SAME | DONG-A PHARMACEUTICAL CO., LTD. (KR) | 1994-03-17 | — | — | WO | disclosed |
| EP-0182213-B1 | CARBAPENEM COMPOUNDS AND PRODUCTION THEREOF | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1990-09-26 | — | — | EP | disclosed |
| EP-0002564-B1 | DERIVATIVES OF 7-OXO-1-AZABICYCLO(3.2.0)-HEPT-2-ENE-2-CARBOXYLIC ACID, THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES | BEECHAM GROUP PLC (GB) | 1984-06-20 | — | — | EP | disclosed |
| US-4347181-A | Intermediates for producing bicyclic β-lactam-antibiotics | BEECHAM GROUP LIMITED (GB) | 1982-08-31 | — | — | US | disclosed |
| US-4289696-A | BETA-LACTAMASE INHIBITORY AGENTS WHICH ENHANCE ACTIVITY OF A PENICICILLIN OR CEPHALOSPORIN | BEECHAM GROUP LIMITED (GB) | 1981-09-15 | — | — | US | disclosed |
| US-4223038-A | THIENAMYCINS | BEECHAM GROUP LIMITED (GB) | 1980-09-16 | — | — | US | disclosed |
| US-4196211-A | ANTIBIOTIC | MERCK & CO., INC. (US) | 1980-04-01 | — | — | US | disclosed |
| US-4196211-A | ANTIBIOTIC | MERCK & CO., INC. (US) | 1980-04-01 | — | — | US | disclosed |
| US-4196211-A | ANTIBIOTIC | MERCK & CO., INC. (US) | 1980-04-01 | — | — | US | disclosed |
| EP-0002564-A1 | Derivatives of 7-oxo-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid, their preparation, pharmaceutical compositions containing them and intermediates | BEECHAM GROUP PLC (GB) | 1979-06-27 | — | — | EP | disclosed |