Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.58 |
| ▸ | PI4KA | P42356 | 5/20 | 0.58 |
| ▸ | PI4K2B | Q8TCG2 | 5/20 | 0.58 |
| ▸ | PI4K2A | Q9BTU6 | 5/20 | 0.58 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9373702 | 0.84 | PI4KA (0.60) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL13269011 | 0.84 | ADORA2A (0.65) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL13268766 | 0.84 | ADORA2A (0.65) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL13269043 | 0.80 | ADORA2A (0.62) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL13268709 | 0.80 | ADORA2A (0.62) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL7436865 | 0.78 | ADORA2A (0.50) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL24205121 | 0.76 | ADORA2A (0.77) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL18521145 | 0.76 | ADORA2A (0.77) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL5360808 | 0.74 | ADORA2A (0.59) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL22474983 | 0.74 | ADORA2A (0.69) | ADORA2API4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2700638-A1 | Purine analogs | The Regents Of the University of California (US) | 2014-02-26 | — | — | EP | disclosed |
| EP-2029597-A2 | PURINE ANALOGS | The Regents of the University of California (US) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007142755-A2 | PURINE ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-12-13 | — | — | WO | disclosed |