Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 5/20 | 0.60 |
| ▸ | PI4K2B | Q8TCG2 | 5/20 | 0.60 |
| ▸ | PI4K2A | Q9BTU6 | 5/20 | 0.60 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.60 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.60 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4245944 | 0.84 | ADORA2A (0.58) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL13269011 | 0.82 | ADORA2A (0.65) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL28018567 | 0.82 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL13268766 | 0.82 | ADORA2A (0.65) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL28731072 | 0.79 | ADORA2A (0.69) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL13269043 | 0.79 | ADORA2A (0.62) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL13268709 | 0.79 | ADORA2A (0.62) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL7436865 | 0.77 | ADORA2A (0.50) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL754007 | 0.76 | ADORA2A (1.00) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| Hydrochloric Acid SCHEMBL30881556 | 0.74 | ADORA2A (0.96) | PI4KAPI4K2BPI4K2API4KBADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399653-B1 | Anticonvulsant triazolo[4,5-c]pyridine derivatives | WELLCOME FOUND (GB) | 1994-10-19 | — | — | EP | disclosed |
| US-5240937-A | Treatment of epilepsy | BURROUGHS WELLCOME CO. (US) | 1993-08-31 | — | — | US | disclosed |
| US-5166209-A | Triazolopyridine compounds as anticonvulsants for treatment of epilepsy | BURROUGHS WELLCOME CO. (US) | 1992-11-24 | — | — | US | disclosed |
| US-5095018-A | Anticonvulsants | BURROUGHS WELLCOME CO. (US) | 1992-03-10 | — | — | US | disclosed |
| EP-0399653-A1 | Anticonvulsant triazolo[4,5-c]pyridine derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-11-28 | — | — | EP | disclosed |