SCHEMBL4246129

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3872439	0.85	TLR7 (0.47)	TLR7GAAMEN1KMT2ABRD4
	SCHEMBL4245048	0.85	TLR7 (0.59)	TLR7
	SCHEMBL5807920	0.85	TLR7 (0.43)	TLR7MEN1KMT2ABRD4RAB9A
	SCHEMBL16188207	0.84	TLR7 (0.39)	TLR7
	SCHEMBL4241469	0.83	TLR7 (0.40)	TLR7BRD4SMN1; SMN2
	SCHEMBL1486493	0.81	CYP3A4 (0.43)	TLR7MEN1KMT2ARAB9ALMNA
	SCHEMBL4242310	0.81	TLR7 (0.39)	TLR7
	SCHEMBL1952558	0.81	TLR7 (0.49)	TLR7GAAMEN1KMT2ARAB9A
	SCHEMBL1949364	0.81	TLR7 (0.47)	TLR7GAAMEN1KMT2ARAB9A
	SCHEMBL1948228	0.80	TLR7 (0.44)	TLR7GAAMEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.