SCHEMBL4246237

SCHEMBL4246237

CC1OC(C)(C(=O)O)OCC1Cc1ccc2cc(OCc3ccccc3F)ccc2c1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 13/20 0.52
PTPN2 P17706 11/20 0.46
CDC25B P30305 11/20 0.46
PPARG P37231 3/20 0.45
PPARA Q07869 3/20 0.45
MAOB P27338 3/20 0.43
PTPN6 P29350 5/20 0.42
PARP15 Q460N3 1/20 0.41
PARP14 Q460N5 1/20 0.41
PARP10 Q53GL7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4246506 0.89 PPARG (0.49) PPARGPPARAMAOB
SCHEMBL4250702 0.87 PTPN1 (0.57) PTPN1PTPN2CDC25BPPARGPPARA
SCHEMBL4247957 0.87 PTPN1 (0.57) PTPN1PTPN2CDC25BPPARGPPARA
SCHEMBL4247961 0.87 PTPN1 (0.57) PTPN1PTPN2CDC25BPPARGPPARA
SCHEMBL4251665 0.81 PPARG (0.51) PPARGPPARAMAOBPARP10
SCHEMBL4246884 0.80 PPARG (0.60) PTPN1PPARGPPARAMAOBPARP15
SCHEMBL4243635 0.80 PPARG (0.60) PTPN1PPARGPPARAMAOBPARP15
SCHEMBL4243636 0.80 PPARG (0.60) PTPN1PPARGPPARAMAOBPARP15
SCHEMBL4246234 0.80 PTPN1 (0.52) PTPN1PTPN2CDC25BPPARGPPARA
SCHEMBL4243352 0.75 PPARA (0.61) PPARGPPARAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090012069-A1 Novel Antidiabetic Compounds CADILA HEALTHCARE LIMITED (IN) 2009-01-08 US claimed
US-20090012069-A1 Novel Antidiabetic Compounds CADILA HEALTHCARE LIMITED (IN) 2009-01-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090012069-A1 Novel Antidiabetic Compounds GPR119, SLC5A1, SLC5A2 PTPN1 724/4885PTPN2 852/4885CDC25B 2617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.