SCHEMBL4246719

SCHEMBL4246719

CC(C)c1cc(C(C)C)c(S(=O)(=O)CS(=O)(=O)c2c(C(C)C)cc(C(C)C)cc2C(C)C)c(C(C)C)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 6/20 0.62
FABP3 P05413 2/20 0.62
FABP5 Q01469 1/20 0.62
ALDH1A1 P00352 1/20 0.44
GAA P10253 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
TDP1 Q9NUW8 1/20 0.38
NR3C1 P04150 1/20 0.38
HDAC1 Q13547 1/20 0.38
SOAT2 O75908 1/20 0.35
MYC P01106 1/20 0.35
SOAT1 P35610 1/20 0.35
MAP2K3 P46734 1/20 0.35
EPHX2 P34913 1/20 0.35
PIK3CD O00329 1/20 0.35
PIK3CA P42336 1/20 0.35
PIK3CB P42338 1/20 0.35
PIK3CG P48736 1/20 0.35
ENPP3 O14638 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24682303 0.82 FABP4 (0.56) FABP4FABP3FABP5ALDH1A1GAA
SCHEMBL8989764 0.80 FABP4 (0.69) FABP4FABP3FABP5ALDH1A1GAA
SCHEMBL456464 0.78 FABP4 (0.67) FABP4FABP3FABP5ALDH1A1GAA
SCHEMBL162818 0.78 FABP4 (0.67) FABP4FABP3FABP5ALDH1A1GAA
SCHEMBL8243105 0.78 FABP4 (0.67) FABP4FABP3FABP5ALDH1A1GAA
SCHEMBL12983353 0.77 FABP4 (0.64) FABP4FABP3FABP5ALDH1A1GAA
SCHEMBL86091 0.77 FABP4 (1.00) FABP4FABP3FABP5ALDH1A1GAA
SCHEMBL15139221 0.77 FABP4 (0.64) FABP4FABP3FABP5ALDH1A1GAA
SCHEMBL17318094 0.77 FABP4 (0.64) FABP4FABP3FABP5ALDH1A1GAA
SCHEMBL1069046 0.77 FABP4 (0.64) FABP4FABP3FABP5ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7638654-B2 1-fluoro-1, 1-bis-(phenylsulfonyl)methane and production method thereof NAGOYA INSTITUTE OF TECHNOLOGY (JP) 2009-12-29 US disclosed
US-20090131723-A1 1-Fluoro-1,1-Bis-(Phenylsulfonyl)Methane and Production Method Thereof TOSOH F-TECH, INC. (JP) 2009-05-21 US disclosed
EP-1992612-A1 1-FLUORO-1,1-BIS(PHENYLSULFONYL)METHANE AND METHOD FOR PRODUCING SAME NAGOYA INSTITUTE OF TECHNOLOGY (JP) 2008-11-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090131723-A1 1-Fluoro-1,1-Bis-(Phenylsulfonyl)Methane and Production Method Thereof CYP2S1, ARSA, MSMO1 FABP4 2448/4885FABP3 2918/4885FABP5 1683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.