SCHEMBL4246764

SCHEMBL4246764

CCOC(=O)C1CCc2cccc(N)c2O1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.52
CYP4A11 Q02928 1/20 0.52
L3MBTL1 Q9Y468 2/20 0.47
TDP1 Q9NUW8 3/20 0.46
CTDSP1 Q9GZU7 1/20 0.42
LGMN Q99538 2/20 0.39
ALDH1A1 P00352 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
ATM Q13315 1/20 0.38
TSHR P16473 1/20 0.36
KDM4E B2RXH2 1/20 0.36
POLB P06746 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14046828 1.00 CYP4F2 (0.52) CYP4F2CYP4A11L3MBTL1TDP1CTDSP1
SCHEMBL30982179 1.00 CYP4F2 (0.52) CYP4F2CYP4A11L3MBTL1TDP1CTDSP1
SCHEMBL8314473 0.86 CYP4F2 (0.56) CYP4F2CYP4A11L3MBTL1TDP1CTDSP1
SCHEMBL24496718 0.85 NFKB1 (0.41) CYP4F2CYP4A11L3MBTL1TDP1ALDH1A1
SCHEMBL24496712 0.85 NFKB1 (0.41) CYP4F2CYP4A11L3MBTL1TDP1ALDH1A1
SCHEMBL29588222 0.85 NFKB1 (0.41) CYP4F2CYP4A11L3MBTL1TDP1ALDH1A1
SCHEMBL5730179 0.85 CYP4F2 (0.52) CYP4F2CYP4A11L3MBTL1TDP1CTDSP1
SCHEMBL7314503 0.84 TDP1 (0.56) CYP4F2CYP4A11L3MBTL1TDP1CTDSP1
SCHEMBL8583246 0.82 CYP4F2 (0.50) CYP4F2CYP4A11L3MBTL1TDP1CTDSP1
SCHEMBL14092138 0.81 CYP4F2 (0.52) CYP4F2CYP4A11L3MBTL1TDP1CTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2105432-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
EP-2105431-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
EP-1867626-A2 Process for producing chromone compound Sumitomo Chemical Company, Limited (JP) 2007-12-19 EP disclosed
US-20060217565-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-09-28 US disclosed
US-7094914-B2 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-08-22 US disclosed
US-20050085664-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LMITED (JP) 2005-04-21 US disclosed
EP-1479667-A1 PROCESS FOR PRODUCING CHROMONE COMPOUND Sumitomo Chemical Company, Limited (JP) 2004-11-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050085664-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL CYP4F2 27/4885CYP4A11 18/4885L3MBTL1 3519/4885
US-20060217565-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL CYP4F2 27/4885CYP4A11 18/4885L3MBTL1 3519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.