Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 20/20 | 1.00 |
| ▸ | HSP90AB1 | P08238 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3127058 | 1.00 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1 | |
| SCHEMBL3124809 | 1.00 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1 | |
| SCHEMBL3739499 | 0.95 | HSP90AA1 (0.91) | HSP90AA1HSP90AB1 | |
| SCHEMBL1899198 | 0.94 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1 | |
| SCHEMBL29360648 | 0.94 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1 | |
| SCHEMBL3120563 | 0.94 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1 | |
| SCHEMBL3117563 | 0.94 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1 | |
| SCHEMBL30132824 | 0.94 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1 | |
| SCHEMBL13895459 | 0.94 | HSP90AA1 (0.88) | HSP90AA1HSP90AB1 | |
| SCHEMBL13895607 | 0.94 | HSP90AA1 (0.88) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038041-A2 | THERAPEUTIC COMPOUNDS AND THEIR USE IN CANCER | Myriad Genetics, Inc. (US) | 2009-03-25 | — | — | EP | disclosed |
| WO-2007134298-A2 | THERAPEUTIC COMPOUNDS AND THEIR USE IN CANCER | MYRIAD GENETICS, INC. (US) | 2007-11-22 | — | — | WO | disclosed |