SCHEMBL29360648

SCHEMBL29360648

C[C@H](O)C(=O)N1CCC(CCn2c(Sc3cc4c(cc3Br)OCO4)nc3c(N)ncnc32)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 20/20 1.00
HSP90AB1 P08238 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1899198 1.00 HSP90AA1 (1.00) HSP90AA1HSP90AB1
SCHEMBL3120563 1.00 HSP90AA1 (1.00) HSP90AA1HSP90AB1
SCHEMBL3117563 1.00 HSP90AA1 (1.00) HSP90AA1HSP90AB1
SCHEMBL30132824 1.00 HSP90AA1 (1.00) HSP90AA1HSP90AB1
SCHEMBL13730578 0.96 HSP90AA1 (1.00) HSP90AA1HSP90AB1
SCHEMBL3520660 0.96 HSP90AA1 (1.00) HSP90AA1HSP90AB1
SCHEMBL3525506 0.96 HSP90AA1 (1.00) HSP90AA1HSP90AB1
SCHEMBL3739499 0.95 HSP90AA1 (0.91) HSP90AA1HSP90AB1
SCHEMBL14733547 0.94 HSP90AA1 (0.89) HSP90AA1HSP90AB1
SCHEMBL3124809 0.94 HSP90AA1 (1.00) HSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 319 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250387492-A1 HSP90-TARGETING CONJUGATES AND FORMULATIONS THEREOF FUSION PHARMACEUTICALS INC (CA) 2025-12-25 US claimed
EP-4667458-A1 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF CANCER, COMPRISING SOS1 INHIBITOR AND ANTICANCER DRUG Kanaph Therapeutics Inc. (KR) 2025-12-24 EP claimed
CN-119236123-A HSP 90-targeting conjugates and formulations thereof 融合制药公司 2025-01-03 CN claimed
WO-2024172631-A1 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF CANCER, COMPRISING SOS1 INHIBITOR AND ANTICANCER DRUG 주식회사 카나프테라퓨틱스 2024-08-22 WO claimed
EP-3689411-B1 METHOD FOR MANUFACTURING A MICRONEEDLE ARRAY FUJIFILM CORP (JP) 2024-04-24 EP claimed
CN-116077660-A A method for treating cancer 杭州百可生物科技有限公司 2023-05-09 CN claimed
CN-115990253-A Method for reducing drug resistance of cancer patient 杭州百可生物科技有限公司 2023-04-21 CN claimed
CN-115957328-A Pharmaceutical composition for treating leukemia and leukemia treatment method 杭州百可生物科技有限公司 2023-04-14 CN claimed
US-20220243280-A1 NTRK FUSION MOLECULES AND USES THEREOF FOUNDATION MEDICINE, INC. (US) 2022-08-04 US claimed
US-20220096640-A1 HSP90-TARGETING CONJUGATES AND FORMULATIONS THEREOF TVA (ABC), LLC 2022-03-31 US claimed
WO-2022047008-A1 HSP90-BINDING CONJUGATES AND FORMULATIONS THEREOF TARVEDA THERAPEUTICS, INC. (US) 2022-03-03 WO claimed
US-20220031853-A1 HSP90-TARGETING CONJUGATES AND FORMULATIONS THEREOF TVA (ABC), LLC 2022-02-03 US claimed
US-20260144196-A1 AGRICULTURAL GREENHOUSE, PLANT CULTIVATION METHOD USING THE SAME, AND HEAT-RAY REFLECTING FILM STRUCTURE TOYOBO CO., LTD. (JP) 2026-05-28 US disclosed
US-12637720-B2 Molecular subtyping of small cell lung cancer to predict therapeutic responses BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2026-05-26 US disclosed
US-12616759-B2 Uses of labeled HSP90 inhibitors SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 2026-05-05 US disclosed
US-12606746-B2 Composition, optically anisotropic layer, liquid crystal cell, liquid crystal display device, sensor, lens, switching element, isolator, and camera FUJIFILM CORPORATION (JP) 2026-04-21 US disclosed
US-11241500-B2 HSP90-targeting conjugates and formulations thereof TARVEDA THERAPEUTICS, INC. (US) 2022-02-08 US disclosed
US-20220031853-A1 HSP90-TARGETING CONJUGATES AND FORMULATIONS THEREOF TVA (ABC), LLC 2022-02-03 US disclosed
CN-114007671-A Methods and compositions for treating chronic inflammatory injury, metaplasia, dysplasia and cancer of epithelial tissue 休斯敦大学体系 2022-02-01 CN disclosed
WO-2022019920-A1 TREATMENT OF CANCERS USING PI3 KINASE ISOFORM MODULATORS VERASTEM, INC. (US) 2022-01-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220243280-A1 NTRK FUSION MOLECULES AND USES THEREOF NTRK1, NTRK3, NTRK2 HSP90AA1 1786/4885HSP90AB1 1768/4885
US-20220096640-A1 HSP90-TARGETING CONJUGATES AND FORMULATIONS THEREOF HSP90AB1, HSP90AA1, HSP90B1 HSP90AA1 2/4885HSP90AB1 1/4885
US-12606746-B2 Composition, optically anisotropic layer, liquid crystal cell, liquid crystal display device, sensor, lens, switching element, isolator, and camera CRYAA, SSB, UACA HSP90AA1 1606/4885HSP90AB1 2306/4885
US-20260144196-A1 AGRICULTURAL GREENHOUSE, PLANT CULTIVATION METHOD USING THE SAME, AND HEAT-RAY REFLECTING FILM STRUCTURE CRY2, CRY1, WAPL HSP90AA1 680/4885HSP90AB1 480/4885
US-11241500-B2 HSP90-targeting conjugates and formulations thereof HSP90AB1, HSP90AA1, HSP90B1 HSP90AA1 2/4885HSP90AB1 1/4885
US-12616759-B2 Uses of labeled HSP90 inhibitors HSP90AB1, HSP90B1, HSP90AB2P HSP90AA1 4/4885HSP90AB1 1/4885
US-20220031853-A1 HSP90-TARGETING CONJUGATES AND FORMULATIONS THEREOF HSP90AB1, HSP90AA1, HSP90B1 HSP90AA1 2/4885HSP90AB1 1/4885
US-20250387492-A1 HSP90-TARGETING CONJUGATES AND FORMULATIONS THEREOF HSP90AB1, HSP90AB2P, HSP90AA1 HSP90AA1 3/4885HSP90AB1 1/4885
US-12637720-B2 Molecular subtyping of small cell lung cancer to predict therapeutic responses POU2F1, POU2F2, PARP2 HSP90AA1 3101/4885HSP90AB1 2576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.