Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MRE11 | P49959 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4246812 | 1.00 | XDH (0.53) | XDHPOLBHDAC4HDAC8PTPN1 | |
| SCHEMBL8876327 | 0.91 | HDAC4 (0.58) | POLBHDAC4HDAC8PTPN1HPGD | |
| SCHEMBL8876321 | 0.91 | HDAC4 (0.58) | POLBHDAC4HDAC8PTPN1HPGD | |
| SCHEMBL16131327 | 0.78 | KMT2A (0.55) | XDHPOLBPTPN1HPGDMEN1 | |
| SCHEMBL8876624 | 0.75 | HPGD (0.81) | POLBHDAC4HDAC8PTPN1HPGD | |
| SCHEMBL8876632 | 0.75 | HPGD (0.81) | POLBHDAC4HDAC8PTPN1HPGD | |
| SCHEMBL31556124 | 0.75 | PTPN1 (0.56) | PTPN1MAOBRAB9APARP15PARP10 | |
| SCHEMBL4244280 | 0.75 | PTPN1 (0.56) | PTPN1MAOBRAB9APARP15PARP10 | |
| SCHEMBL15422022 | 0.74 | HPGD (0.81) | XDHPOLBPTPN1HPGDMAOA | |
| SCHEMBL15422023 | 0.74 | HPGD (0.81) | XDHPOLBPTPN1HPGDMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2009234930-A | 2-IMINO-4-THIAZOLIDINONE DERIVATIVE AND METHOD FOR PRODUCING 2,4-THIAZOLIDINEDIONE DERIVATIVE | OHARA YAKUHIN KOGYO KK | 2009-10-15 | — | — | JP | disclosed |