SCHEMBL4247422

SCHEMBL4247422

CC(c1ccc(O)cc1)C(C)c1ccc(O)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 10/20 0.68
ESR2 Q92731 9/20 0.68
PDCD1 Q15116 1/20 0.68
CD274 Q9NZQ7 1/20 0.68
LMNA P02545 2/20 0.52
CYP3A4 P08684 2/20 0.52
MAPT P10636 2/20 0.52
ALOX15 P16050 2/20 0.52
CYP2C9 P11712 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
CYP1A2 P05177 1/20 0.52
PGR P06401 1/20 0.52
CHRM2 P08172 1/20 0.52
ADORA3 P0DMS8 1/20 0.52
AR P10275 1/20 0.52
CYP2D6 P10635 1/20 0.52
CHRM1 P11229 1/20 0.52
DRD1 P21728 1/20 0.52
TBXA2R P21731 1/20 0.52
PTGS1 P23219 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30753092 1.00 ESR1 (0.68) ESR1ESR2PDCD1CD274LMNA
SCHEMBL29351491 1.00 ESR1 (0.68) ESR1ESR2PDCD1CD274LMNA
SCHEMBL11949347 1.00 ESR1 (0.68) ESR1ESR2PDCD1CD274LMNA
SCHEMBL20371199 0.88 ESR1 (0.62) ESR1ESR2PDCD1CD274LMNA
SCHEMBL2631307 0.88 ESR1 (0.62) ESR1ESR2PDCD1CD274LMNA
SCHEMBL1697224 0.86 ESR1 (0.59) ESR1ESR2PDCD1CD274LMNA
SCHEMBL16803087 0.85 ESR1 (0.57) ESR1ESR2PDCD1CD274LMNA
SCHEMBL13898476 0.84 ESR1 (0.56) ESR1ESR2PDCD1CD274LMNA
SCHEMBL10751699 0.84 ESR1 (0.56) ESR1ESR2PDCD1CD274LMNA
SCHEMBL14156465 0.84 ESR1 (0.56) ESR1ESR2PDCD1CD274LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070276034-A1 Compounds, compositions and methods for the treatment of synucleinopathies PROTEOTECH, INC. 2007-11-29 US claimed
US-20230203234-A1 HOLLOW MICROBALLOONS TOKUYAMA CORPORATION (JP) 2023-06-29 US disclosed
US-20230151179-A1 HOLLOW MICROBALLOONS FOR CMP POLISHING PAD TOKUYAMA CORPORATION (JP) 2023-05-18 US disclosed
US-9206308-B2 Epoxy resin composition for prepreg, prepreg, and multilayer printed circuit board PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2015-12-08 US disclosed
US-20130096233-A1 EPOXY RESIN COMPOSITION FOR PREPREG, PREPREG, AND MULTILAYER PRINTED CIRCUIT BOARD PANASONIC CORPORATION (JP) 2013-04-18 US disclosed
US-20120107725-A1 Solid Polymer Electrolyte Composition, and Ion-Exchange Membrane, Membrane Electrode Assembly and Fuel Cell TOYO BOSEKI KABUSHIKI KAISHA (JP) 2012-05-03 US disclosed
US-20120107725-A1 Solid Polymer Electrolyte Composition, and Ion-Exchange Membrane, Membrane Electrode Assembly and Fuel Cell TOYO BOSEKI KABUSHIKI KAISHA (JP) 2012-05-03 US disclosed
US-7556902-B2 Aromatic polyester resin, and electrophotographic photoconductor and image forming apparatus using thereof RICOH COMPANY, LTD. (JP) 2009-07-07 US disclosed
US-7348113-B2 Electrophotographic photoconductor comprising a polycarbonate resin having a dihydroxy diphenyl ether unit RICOH COMPANY, LTD. (JP) 2008-03-25 US disclosed
EP-1660556-A1 COPOLYETHERIMIDES GENERAL ELECTRIC COMPANY (US) 2006-05-31 EP disclosed
US-20060046169-A1 Aromatic polyester resin, and electrophotographic photoconductor and image forming apparatus using thereof RICOH COMPANY, LTD. (JP) 2006-03-02 US disclosed
US-20050106483-A1 Aromatic polycarbonate resin, electrophotographic photoconductor, dihydroxy diphenyl ether compound, and process of manufacturing dihydroxy diphenyl ether compound RICOH COMPANY, LTD. (JP) 2005-05-19 US disclosed
WO-2005023901-A1 COPOLYETHERIMIDES GENERAL ELECTRIC COMPANY (US) 2005-03-17 WO disclosed
EP-0616002-B1 PROCESS FOR PRODUCING POLYCARBONATE POWDER IDEMITSU PETROCHEMICAL CO (JP) 1998-03-04 EP disclosed
US-5475084-A Ejecting solution mixture of polycarbonate, solvent and steam through mixing nozzle IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1995-12-12 US disclosed
EP-0616002-A1 PROCESS FOR PRODUCING POLYCARBONATE POWDER IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-09-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070276034-A1 Compounds, compositions and methods for the treatment of synucleinopathies SNCA, PARK7, COMT ESR1 4495/4885ESR2 3651/4885PDCD1 1961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.