SCHEMBL4247912

SCHEMBL4247912

CCOC(=O)/C=C(/Cl)C(=O)OCC

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 3/20 0.63
HCAR2 Q8TDS4 1/20 0.43
GLO1 Q04760 1/20 0.42
ALDH1A1 P00352 4/20 0.39
CYP2D6 P10635 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
LMNA P02545 2/20 0.37
HSD17B10 Q99714 1/20 0.37
TSHR P16473 1/20 0.36
MAPT P10636 4/20 0.36
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
ALOX15 P16050 1/20 0.36
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
SOAT1 P35610 1/20 0.36
EGLN1 Q9GZT9 1/20 0.35
CYP2C9 P11712 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4109423 1.00 NPSR1 (0.63) NPSR1HCAR2GLO1ALDH1A1CYP2D6
SCHEMBL4109419 1.00 NPSR1 (0.63) NPSR1HCAR2GLO1ALDH1A1CYP2D6
SCHEMBL11149236 0.88 NPSR1 (0.48) NPSR1HCAR2GLO1ALDH1A1CYP2D6
SCHEMBL11149240 0.88 NPSR1 (0.53) NPSR1HCAR2GLO1ALDH1A1CYP2D6
SCHEMBL11149232 0.88 NPSR1 (0.53) NPSR1HCAR2GLO1ALDH1A1CYP2D6
SCHEMBL4115120 0.83 NPSR1 (0.47) NPSR1HCAR2GLO1ALDH1A1CYP2D6
SCHEMBL4115115 0.83 NPSR1 (0.47) NPSR1HCAR2GLO1ALDH1A1CYP2D6
SCHEMBL27385701 0.83 NPSR1 (0.47) NPSR1HCAR2GLO1ALDH1A1CYP2D6
SCHEMBL9839727 0.80 NPSR1 (0.59) NPSR1HCAR2GLO1ALDH1A1CYP2D6
SCHEMBL9839729 0.80 NPSR1 (0.59) NPSR1HCAR2GLO1ALDH1A1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0402561-B1 Process for the manufacture of anilinofumarate via chloromaleate or chlorofumarate or mixtures thereof AMERICAN CYANAMID CO (US) 1994-10-05 EP claimed
CN-103804660-B A kind of unsaturated aliphatic-polylactic-acid block copolymer and preparation method thereof CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) 2016-02-03 CN disclosed
CN-104725620-A Unsaturated polylactic acid segmented copolymer and preparation method thereof CHANGCHUN APPLIED CHEMISTRY 2015-06-24 CN disclosed
EP-2105432-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
EP-2105431-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
CN-100358927-C Aqueous polymer composition ROHM & HAAS (US) 2008-01-02 CN disclosed
EP-1867626-A2 Process for producing chromone compound Sumitomo Chemical Company, Limited (JP) 2007-12-19 EP disclosed
US-7265166-B2 Aqueous polymer composition ROHM AND HAAS COMPANY (US) 2007-09-04 US disclosed
US-20060217565-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-09-28 US disclosed
US-7094914-B2 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-08-22 US disclosed
WO-1993019128-A2 POLYMERS AND POLYMER BLENDS MODIFIED WITH POLY(PHENYLENE ETHER) THE DOW CHEMICAL COMPANY (US) 1993-09-30 WO disclosed
WO-1993018090-A1 IGNITION RESISTANT POLYCARBONATE BLENDS THE DOW CHEMICAL COMPANY (US) 1993-09-16 WO disclosed
EP-0530276-A1 POLYCARBONATE/POLYESTER BLENDS WITH IMPROVED THERMAL MELT STABILITY THE DOW CHEMICAL COMPANY (US) 1993-03-10 EP disclosed
EP-0525051-A1 POLYCARBONATE/AROMATIC POLYESTER BLENDS CONTAINING AN OLEFINIC MODIFIER. DOW CHEMICAL CO (US) 1993-02-03 EP disclosed
CN-1062724-A Replace or do not have replacement-2, the method for 3-pyridine dicarboxylate by chloromaleic acid ester or chlorofumaric acid ester or the preparation of its mixture AMERICAN CYANAMID CO (US) 1992-07-15 CN disclosed
WO-1991018052-A1 POLYCARBONATE/POLYESTER BLENDS WITH IMPROVED THERMAL MELT STABILITY THE DOW CHEMICAL COMPANY (US) 1991-11-28 WO disclosed
WO-1991016379-A1 POLYCARBONATE/AROMATIC POLYESTER BLENDS CONTAINING AN OLEFINIC MODIFIER THE DOW CHEMICAL COMPANY (US) 1991-10-31 WO disclosed
EP-0396113-A2 Grafted olefin copolymers and polycarbonate blends modified with a grafted olefin copolymer THE DOW CHEMICAL COMPANY (US) 1990-11-07 EP disclosed
US-4929673-A POLYCARBONYLS, IMPACT STRENGTH RUBBER TOUGHENERS THE DOW CHEMICAL COMPANY (US) 1990-05-29 US disclosed
US-3948960-A ADDITION, HYDROGEN PEROXIDE, INTRAPHASE PONY INDUSTRIES, INC., A CORP. OF DE 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060217565-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL NPSR1 937/4885HCAR2 354/4885GLO1 3348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.