SCHEMBL4247950

SCHEMBL4247950

CCCCCOC(=O)C=C(Cl)C(=O)OCCCCC

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.51
ATM Q13315 1/20 0.50
TSHR P16473 4/20 0.49
HPGD P15428 1/20 0.47
NAAA Q02083 1/20 0.44
NPSR1 Q6W5P4 2/20 0.42
RAD52 P43351 1/20 0.42
EPHX1 P07099 1/20 0.42
ALDH1A1 P00352 1/20 0.39
APP P05067 3/20 0.39
LMNA P02545 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HTT P42858 1/20 0.39
MAPT P10636 1/20 0.39
RAB9A P51151 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4247945 1.00 HCAR2 (0.51) HCAR2ATMTSHRHPGDNAAA
SCHEMBL4253657 1.00 HCAR2 (0.51) HCAR2ATMTSHRHPGDNAAA
SCHEMBL4254666 0.98 HCAR2 (0.53) HCAR2ATMTSHRHPGDNAAA
SCHEMBL4249695 0.98 HCAR2 (0.53) HCAR2ATMTSHRHPGDNAAA
SCHEMBL4249688 0.98 HCAR2 (0.53) HCAR2ATMTSHRHPGDNAAA
SCHEMBL4254653 0.95 ATM (0.57) HCAR2ATMTSHRHPGDNAAA
SCHEMBL4251461 0.95 ATM (0.57) HCAR2ATMTSHRHPGDNAAA
SCHEMBL4251457 0.95 ATM (0.57) HCAR2ATMTSHRHPGDNAAA
SCHEMBL4256586 0.87 HCAR2 (0.47) HCAR2ATMTSHRHPGDNPSR1
SCHEMBL4253375 0.87 HCAR2 (0.47) HCAR2ATMTSHRHPGDNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2105432-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
EP-2105431-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
EP-1867626-A2 Process for producing chromone compound Sumitomo Chemical Company, Limited (JP) 2007-12-19 EP disclosed
US-7094914-B2 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-08-22 US disclosed
US-20050085664-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LMITED (JP) 2005-04-21 US disclosed
EP-1479667-A1 PROCESS FOR PRODUCING CHROMONE COMPOUND Sumitomo Chemical Company, Limited (JP) 2004-11-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050085664-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL HCAR2 354/4885ATM 1987/4885TSHR 1710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.