SCHEMBL4254666

SCHEMBL4254666

CCCCCCOC(=O)/C=C(\Cl)C(=O)OCCCCCC

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.53
TSHR P16473 5/20 0.51
ATM Q13315 1/20 0.48
NAAA Q02083 1/20 0.47
HPGD P15428 1/20 0.46
RAD52 P43351 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
EPHX1 P07099 1/20 0.44
LMNA P02545 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HTT P42858 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP3A4 P08684 1/20 0.41
APP P05067 3/20 0.40
FAAH O00519 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4249695 1.00 HCAR2 (0.53) HCAR2TSHRATMNAAAHPGD
SCHEMBL4249688 1.00 HCAR2 (0.53) HCAR2TSHRATMNAAAHPGD
SCHEMBL4247945 0.98 HCAR2 (0.51) HCAR2TSHRATMNAAAHPGD
SCHEMBL4253657 0.98 HCAR2 (0.51) HCAR2TSHRATMNAAAHPGD
SCHEMBL4247950 0.98 HCAR2 (0.51) HCAR2TSHRATMNAAAHPGD
SCHEMBL4251457 0.93 ATM (0.57) HCAR2TSHRATMNAAAHPGD
SCHEMBL4251461 0.93 ATM (0.57) HCAR2TSHRATMNAAAHPGD
SCHEMBL4254653 0.93 ATM (0.57) HCAR2TSHRATMNAAAHPGD
SCHEMBL4256586 0.85 HCAR2 (0.47) HCAR2TSHRATMHPGDNPSR1
SCHEMBL4253375 0.85 HCAR2 (0.47) HCAR2TSHRATMHPGDNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2105431-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
EP-2105432-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
EP-1867626-A2 Process for producing chromone compound Sumitomo Chemical Company, Limited (JP) 2007-12-19 EP disclosed
US-20060217565-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-09-28 US disclosed
US-7094914-B2 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-08-22 US disclosed
US-20050085664-A1 Process for producing chromone compound SUMITOMO CHEMICAL COMPANY, LMITED (JP) 2005-04-21 US disclosed
EP-1479667-A1 PROCESS FOR PRODUCING CHROMONE COMPOUND Sumitomo Chemical Company, Limited (JP) 2004-11-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050085664-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL HCAR2 354/4885TSHR 1710/4885ATM 1987/4885
US-20060217565-A1 Process for producing chromone compound ENY2, CDY1; CDY1B, CDYL HCAR2 354/4885TSHR 1710/4885ATM 1987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.