SCHEMBL4248141

SCHEMBL4248141

CCOP(=O)(OCC)OCc1cccc(OC)c1

nearest known ligand 0.54

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.54
AGXT P21549 2/20 0.54
MAOB P27338 4/20 0.48
CMA1 P23946 1/20 0.46
TAAR1 Q96RJ0 3/20 0.46
MMP13 P45452 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21875855 0.94 IDO1 (0.61) IDO1AGXTMAOBCMA1TAAR1
SCHEMBL29648388 0.85 TSHR (0.51) IDO1AGXTMAOBTAAR1MMP13
SCHEMBL8210094 0.83 TSHR (0.46)
SCHEMBL11916847 0.82 CYP3A4 (0.50)
SCHEMBL5167661 0.81 IDO1 (0.51) IDO1MAOBTAAR1
SCHEMBL21875857 0.81 IDO1 (0.57) IDO1AGXTMAOBCMA1TAAR1
SCHEMBL4801868 0.81 IDO1 (0.50) IDO1AGXTMAOBCMA1TAAR1
SCHEMBL5521298 0.80 IDO1 (0.48) IDO1AGXTMAOB
SCHEMBL30323683 0.79 CMA1 (0.47) IDO1AGXTCMA1TAAR1MMP13
SCHEMBL4237467 0.79 CMA1 (0.47) IDO1AGXTCMA1TAAR1MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101475451-B Method for synthesizing trans-resveratrol UNIV NANJING NORMAL 2011-10-26 CN claimed
CN-101475451-A Method for synthesizing trans-resveratrol UNIV NANJING NORMAL (CN) 2009-07-08 CN claimed
CN-105541569-A Synthesis method of 1-benzyloxy-2-[2-(3-methoxyphenyl)vinyl]benzene SUZHOU CHENGHE PHARMACEUTICAL & CHEMICAL CO LTD 2016-05-04 CN disclosed
CN-105541566-A Method for synthesizing 1-benzyloxy-2-[2-(3-methoxyphenyl)vinyl]benzene SUZHOU CHENGHE PHARMACEUTICAL & CHEMICAL CO LTD 2016-05-04 CN disclosed
CN-105541564-A New method for synthesizing 1-benzyloxy-2-[2-(3-methoxyphenyl)vinyl]benzene SUZHOU CHENGHE PHARMACEUTICAL & CHEMICAL CO LTD 2016-05-04 CN disclosed
CN-105541565-A Method for preparing 1-benzyloxy-2-[2-(3-methoxyphenyl)vinyl]benzene SUZHOU CHENGHE PHARMACEUTICAL & CHEMICAL CO LTD 2016-05-04 CN disclosed
CN-105503950-A Method for synthesizing m-methoxybenzyl diphenylphosphine oxide TAICANG KASITEMU NEW MAT CO LTD 2016-04-20 CN disclosed
CN-105503954-A Synthetic method of m-methoxy benzyl diphenyl phosphine oxide SUZHOU CHENGHE PHARMACEUTICAL & CHEMICAL CO LTD 2016-04-20 CN disclosed
CN-105503953-A Method for synthesizing 3-methoxybenzyl diphenylphosphine oxide SUZHOU CHENGHE PHARMACEUTICAL & CHEMICAL CO LTD 2016-04-20 CN disclosed
CN-105503951-A Method for one-step synthesis of meta-methoxy benzyl diphenyl phosphine oxide TAICANG KASITEMU NEW MAT CO LTD 2016-04-20 CN disclosed
CN-105503952-A Method for conveniently preparing m-methoxyl benzyl diphenylphosphine oxide SUZHOU CHENGHE PHARMACEUTICAL & CHEMICAL CO LTD 2016-04-20 CN disclosed
CN-105440075-A Method for preparing m-methoxy benzyldiphenylphosphine TAICANG CASS TATUM NEW MAT CO LTD 2016-03-30 CN disclosed
CN-105439828-A Method for synthesizing 1-benzyloxy-2-[2-(3-methoxyphenyl) vinyl]benzene SUZHOU CHENGHE PHARMACEUTICAL & CHEMICAL CO LTD 2016-03-30 CN disclosed
CN-105418677-A Preparation method for 3-methoxybenzyl diphenylphosphine oxide SUZHOU CHENGHE PHARMACEUTICAL & CHEMICAL CO LTD 2016-03-23 CN disclosed
CN-101475451-B Method for synthesizing trans-resveratrol UNIV NANJING NORMAL 2011-10-26 CN disclosed
CN-101875600-A Synthesis method for industrially producing resveratrol CHENGDU XINJI TECHNOLOGY CO LTD 2010-11-03 CN disclosed
CN-101475451-A Method for synthesizing trans-resveratrol UNIV NANJING NORMAL (CN) 2009-07-08 CN disclosed
US-20090170901-A1 Benzoyl Urea Derivatives RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 2009-07-02 US disclosed
EP-1771429-A1 NEW BENZOYL UREA DERIVATIVES RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 2007-04-11 EP disclosed
WO-2006010966-A1 NEW BENZOYL UREA DERIVATIVES Richter Gedeon Vegyészeti Gyár Rt. (HU) 2006-02-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090170901-A1 Benzoyl Urea Derivatives OPRM1, GRIN2C, GRIN3A IDO1 2101/4885AGXT 2703/4885MAOB 399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.