Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 10/20 | 0.48 |
| ▸ | BCHE | P06276 | 5/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4248347 | 0.87 | CHRM2 (0.52) | ACHEBCHEPKM | |
| SCHEMBL4238211 | 0.82 | CHRM2 (0.47) | ACHEBCHEPKM | |
| SCHEMBL4241506 | 0.82 | CHRM2 (0.48) | ACHEBCHEPKM | |
| SCHEMBL4240894 | 0.81 | CHRM2 (0.47) | ACHEBCHEPKM | |
| SCHEMBL4237271 | 0.79 | CHRM2 (0.46) | ACHEBCHEPKM | |
| SCHEMBL4237321 | 0.79 | SIGMAR1 (0.44) | ACHEPKM | |
| SCHEMBL4244214 | 0.79 | KCNH2 (0.45) | ACHEBCHEPKM | |
| SCHEMBL4250571 | 0.78 | CHRM2 (0.52) | ACHE | |
| SCHEMBL4244052 | 0.78 | CHRM2 (0.39) | ACHEBCHEMAOBPKM | |
| SCHEMBL4242091 | 0.77 | CHRM1 (0.43) | ACHEBCHECCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090012116-A1 | Muscarinic Receptor Antagonists | RANBAXY LABORATORIES LIMITED (IN) | 2009-01-08 | — | — | US | claimed |
| US-20090012116-A1 | Muscarinic Receptor Antagonists | RANBAXY LABORATORIES LIMITED (IN) | 2009-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012116-A1 | Muscarinic Receptor Antagonists | CHRM3, CHRM2, CHRM5 | ACHE 108/4885BCHE 258/4885MAOB 411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.