Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.51 |
| ▸ | F2 | P00734 | 3/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | IL1RN | P18510 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11311538 | 0.90 | CYP2C19 (0.49) | CYP2C19MEP1BAKR1C3F2PRSS1 | |
| SCHEMBL35184 | 0.88 | CYP2C19 (0.55) | CYP2C19MEP1BAKR1C3F2PRSS1 | |
| SCHEMBL29453097 | 0.88 | CYP2C19 (0.55) | CYP2C19MEP1BAKR1C3F2PRSS1 | |
| SCHEMBL11196979 | 0.85 | GAA (0.49) | AKR1C3F2PRSS1PRSS2PRSS3 | |
| SCHEMBL31656383 | 0.85 | GAA (0.49) | AKR1C3F2PRSS1PRSS2PRSS3 | |
| SCHEMBL31401215 | 0.85 | CYP2C19 (0.60) | CYP2C19MEP1BAKR1C3F2PRSS1 | |
| SCHEMBL31401049 | 0.85 | CYP2C19 (0.60) | CYP2C19MEP1BAKR1C3F2PRSS1 | |
| SCHEMBL10721937 | 0.83 | F2 (0.55) | CYP2C19MEP1BAKR1C3F2PRSS1 | |
| SCHEMBL4256145 | 0.83 | LOX (0.51) | ALDH1A1CA1CA2KMT2A | |
| Hydrochloric Acid SCHEMBL11481772 | 0.82 | CYP2C19 (0.50) | CYP2C19MEP1BAKR1C3F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | FLECK ROMAN WOLFGANG | 2009-09-10 | — | — | US | disclosed |
| EP-1960367-A2 | SUBSTITUTED PYRAZOLE COMPOUNDS USEFUL AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007067836-A2 | SUBSTITUTED PYRAZOLE COMPOUNDS USEFUL AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227588-A1 | Substituted pyrazole compounds useful as soluble epoxide hyrolase inhibitors | EPHX1, EPHX2, EPX | CYP2C19 229/4885MEP1B 292/4885AKR1C3 490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.