SCHEMBL4248404

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1486736	0.91	BRD4 (0.40)	TLR7BRD4
	SCHEMBL1231939	0.89	DYRK1A (0.45)	TLR7DYRK1ABRD4STING1L3MBTL1
	SCHEMBL4247851	0.87	TLR7 (0.46)	TLR7TLR8DYRK1ABRD4STING1
	SCHEMBL22359571	0.87	TLR7 (0.54)	TLR7TLR8BRD4STING1PIM1
	SCHEMBL1232902	0.87	DYRK1A (0.40)	TLR7DYRK1AL3MBTL1
	SCHEMBL5349692	0.85	TLR7 (0.53)	TLR7TLR8DYRK1APIM1PIM3
	SCHEMBL3865204	0.84	NMT1 (0.45)	L3MBTL1
	SCHEMBL1486668	0.84	TLR7 (0.40)	TLR7TLR8
	SCHEMBL3867677	0.83	BRD4 (0.43)	TLR7BRD4
	SCHEMBL4252232	0.83	SMN1; SMN2 (0.41)	TLR7TLR8DYRK1ABRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.