Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 3/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3968967 | 0.99 | CYP4F2 (0.51) | TDP1L3MBTL1PLA2G4BCYP4F2CYP4A11 | |
| SCHEMBL4568889 | 0.93 | TDP1 (0.55) | TDP1L3MBTL1PLA2G4BCYP4F2CYP4A11 | |
| SCHEMBL4568870 | 0.91 | TDP1 (0.52) | TDP1L3MBTL1PLA2G4BCYP4F2CYP4A11 | |
| SCHEMBL3968426 | 0.91 | CYP4F2 (0.53) | PLA2G4BCYP4F2CYP4A11PPARGPPARA | |
| SCHEMBL4568879 | 0.89 | PPARA (0.52) | TDP1L3MBTL1PLA2G4BCYP4F2CYP4A11 | |
| SCHEMBL4568922 | 0.88 | MAOB (0.51) | TDP1L3MBTL1PLA2G4BTSHR | |
| SCHEMBL4568925 | 0.87 | MAOB (0.53) | TDP1L3MBTL1PLA2G4BBCHETSHR | |
| SCHEMBL4568882 | 0.86 | PPARA (0.52) | TDP1L3MBTL1PLA2G4BCYP4F2CYP4A11 | |
| SCHEMBL13596190 | 0.85 | LTA4H (0.53) | PLA2G4BCYP4F2CYP4A11CNR1CNR2 | |
| SCHEMBL17402430 | 0.85 | TSHR (0.63) | PLA2G4BCNR1CNR2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009045479-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. (US) | 2009-04-09 | — | — | WO | disclosed |