SCHEMBL4249285

SCHEMBL4249285

CCCCCCCCCCCC(Cl)I

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
THRB P10828 1/20 0.44
LMNA P02545 1/20 0.44
DNM1 Q05193 2/20 0.43
OPRM1 P35372 1/20 0.42
ALDH1A1 P00352 1/20 0.41
GPR84 Q9NQS5 3/20 0.39
FDPS P14324 3/20 0.39
SPHK1 Q9NYA1 1/20 0.39
FFAR1 O14842 1/20 0.39
MAPT P10636 1/20 0.38
LCK P06239 1/20 0.38
PPARD Q03181 1/20 0.38
ZDHHC20 Q5W0Z9 1/20 0.38
ZDHHC2 Q9UIJ5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23647946 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL29196267 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL8862242 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL9170032 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL10486904 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL11044577 0.97
SCHEMBL3639922 0.88
SCHEMBL24581696 0.77 DNM1 (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL3194416 0.77 TSHR (0.50) TSHRTHRBLMNADNM1OPRM1
SCHEMBL2507860 0.77 TSHR (0.50) TSHRTHRBLMNADNM1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2953648-A1 NANOPARTICLES CONTAINING A TAXANE AND THEIR USE ANP Technologies, Inc. (US) 2015-12-16 EP claimed
WO-2014123791-A1 NANOPARTICLES CONTAINING A TAXANE AND THEIR USE ANP TECHNOLOGIES, INC. (US) 2014-08-14 WO claimed
CN-110386855-A 1- halogenated dienes and the method for preparing it and 16 carbon diene yl acetate of (9E, 11Z) -9,11- 信越化学工业株式会社 2019-10-29 CN disclosed
US-20090054713-A1 Method for preparing polyolefinic bases of synthetic oils INSTITUT PROBLEM KHIMICHESKOI FIZIKI ROSSIISKOI AKADEMII NAUK (IPKHF RAN) (RU) 2009-02-26 US disclosed
WO-2006071135-A1 METHOD FOR PREPARING POLYIOLEFINIC BASES OF SYNTHETIC OILS INSTITUT PROBLEM KHIMICHESKOI FIZIKI ROSSIISKOI AKADEMII NAUK (IPKHF RAN) (RU) 2006-07-06 WO disclosed