Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | GAA | P10253 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 6/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6688394 | 0.88 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL13797610 | 0.85 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL8063648 | 0.81 | ALDH1A1 (0.82) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL4265033 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL21234442 | 0.80 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2AGAALMNA | |
| Phenyl Phenylcarbamate SCHEMBL27565311 | 0.80 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL23240239 | 0.79 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL14797757 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL27726253 | 0.78 | NPC1 (0.58) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL2475788 | 0.78 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035008-A2 | COMPOSITIONS AND METHODS FOR PREVENTING OR REDUCING POSTOPERATIVE ILEUS AND GASTRIC STASIS IN MAMMALS | Ethicon, Incorporated (US) | 2009-03-18 | — | — | EP | claimed |
| WO-2007146920-A2 | COMPOSITIONS AND METHODS FOR PREVENTING OR REDUCING POSTOPERATIVE ILEUS AND GASTRIC STASIS IN MAMMALS | ETHICON, INC. (US) | 2007-12-21 | — | — | WO | claimed |
| US-20070286892-A1 | COMPOSITIONS AND METHODS FOR PREVENTING OR REDUCING POSTOPERATIVE ILEUS AND GASTRIC STASIS IN MAMMALS | ETHICON, INC. | 2007-12-13 | — | — | US | claimed |
| EP-2035008-A2 | COMPOSITIONS AND METHODS FOR PREVENTING OR REDUCING POSTOPERATIVE ILEUS AND GASTRIC STASIS IN MAMMALS | Ethicon, Incorporated (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007146920-A2 | COMPOSITIONS AND METHODS FOR PREVENTING OR REDUCING POSTOPERATIVE ILEUS AND GASTRIC STASIS IN MAMMALS | ETHICON, INC. (US) | 2007-12-21 | — | — | WO | disclosed |
| US-20070286892-A1 | COMPOSITIONS AND METHODS FOR PREVENTING OR REDUCING POSTOPERATIVE ILEUS AND GASTRIC STASIS IN MAMMALS | ETHICON, INC. | 2007-12-13 | — | — | US | disclosed |