Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 15/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 15/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4241890 | 0.98 | CHRNA7 (0.56) | CHRNA7KCNH2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4246643 | 0.89 | CHRNA7 (0.58) | CHRNA7KCNH2CHRNA1CYP3A4CHRNB2 | |
| SCHEMBL4241926 | 0.88 | CHRNA7 (0.56) | CHRNA7KCNH2CHRNA1CYP3A4CHRNB2 | |
| SCHEMBL4249772 | 0.88 | CHRNA7 (0.58) | CHRNA7KCNH2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4242687 | 0.88 | CHRNA7 (0.54) | CHRNA7KCNH2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4242708 | 0.87 | CHRNA7 (0.56) | CHRNA7KCNH2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4238218 | 0.87 | CHRNA7 (0.53) | CHRNA7KCNH2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4245379 | 0.86 | CHRNA7 (0.57) | CHRNA7KCNH2CHRNA1CYP3A4CHRNB2 | |
| SCHEMBL4241899 | 0.85 | CHRNA7 (0.58) | CHRNA7KCNH2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4239351 | 0.79 | CHRNA7 (0.53) | CHRNA7KCNH2CHRNA1CYP3A4CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105217-A1 | 2-PHENYL-5-AMINO-1,3,4-OXADIAZOLES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105217-A1 | 2-PHENYL-5-AMINO-1,3,4-OXADIAZOLES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | CHRNA7, CHRNA5, CHRNA2 | CHRNA7 1/4885KCNH2 815/4885NPC1 1641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.