⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9725075 | 1.00 | — | — | |
| SCHEMBL8082557 | 1.00 | — | — | |
| SCHEMBL9429261 | 0.97 | MAPT (0.48) | — | |
| SCHEMBL9427876 | 0.97 | MAPT (0.48) | — | |
| SCHEMBL4317995 | 0.97 | — | — | |
| SCHEMBL7751087 | 0.97 | MAPT (0.48) | — | |
| SCHEMBL9427945 | 0.97 | MAPT (0.48) | — | |
| SCHEMBL5573758 | 0.97 | MAPT (0.48) | — | |
| SCHEMBL9427804 | 0.97 | MAPT (0.48) | — | |
| SCHEMBL477998 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024043242-A1 | HEART FAILURE TREATMENT VIA CARDIOTONIC EFFECT BY TRPC3/6/7 CHANNEL ACTIVATION | 国立大学法人九州大学 | 2024-02-29 | — | — | WO | disclosed |
| WO-2023233994-A1 | PHARMACEUTICAL COMPOSITION AND AUTOPHAGY ACTIVATOR | 国立大学法人京都大学 | 2023-12-07 | — | — | WO | disclosed |
| EP-4281072-A1 | FERROPORTIN-INHIBITORS FOR THE USE IN THE TREATMENT OF MYELODYSPLASTIC SYNDROMES (MDS) | VIFOR (INTERNATIONAL) AG (CH) | 2023-11-29 | — | — | EP | disclosed |
| CN-116710091-A | Membrane iron transporter inhibitors for the treatment of myelodysplastic syndrome (MDS) | 威佛（国际）股份公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-110785417-B | Membrane iron transporter inhibitor salts | 威佛（国际）股份公司 | 2023-05-23 | — | — | CN | disclosed |
| US-20220273634-A1 | Ferroportin-Inhibitors For The Use In The Treatment Of Transfusion-Dependent Beta-Thalassemia (TDT) | VIFOR (INTERNATIONAL) AG (CH) | 2022-09-01 | — | — | US | disclosed |
| CN-114765955-A | Methods and compositions for treating sickle cell disease with an iron transporter inhibitor (VIT-2763) | 威佛（国际）股份公司 | 2022-07-19 | — | — | CN | disclosed |
| CN-114668761-A | Novel ferroportin inhibitors | 威佛（国际）股份公司 | 2022-06-28 | — | — | CN | disclosed |
| EP-3999059-A1 | FERROPORTIN-INHIBITORS FOR THE USE IN THE TREATMENT OF TRANSFUSION-DEPENDENT BETA-THALASSEMIA (TDT) | VIFOR (INTERNATIONAL) AG (CH) | 2022-05-25 | — | — | EP | disclosed |
| EP-3999060-A1 | FERROPORTIN-INHIBITORS FOR THE USE IN THE PREVENTION AND TREATMENT OF KIDNEY INJURIES | VIFOR (INTERNATIONAL) AG (CH) | 2022-05-25 | — | — | EP | disclosed |
| EP-0518636-A1 | Liquid crystal compounds and compositions | SANYO CHEMICAL INDUSTRIES LTD. (JP) | 1992-12-16 | — | — | EP | disclosed |
| EP-0517498-A1 | Liquid crystal compounds and compositions | SANYO CHEMICAL INDUSTRIES LTD. (JP) | 1992-12-09 | — | — | EP | disclosed |
| US-5160662-A | Improved response times | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 1992-11-03 | — | — | US | disclosed |
| US-5013847-A | Insecticides, miticides, nematocides | BASF AKTIENGESELLSCHAFT (DE) | 1991-05-07 | — | — | US | disclosed |
| EP-0409634-A2 | Liquid crystal compounds and optically active compounds | SANYO CHEMICAL INDUSTRIES LTD. (JP) | 1991-01-23 | — | — | EP | disclosed |
| US-4985590-A | Optically active benzene derivatives and process for preparation thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0385692-A2 | Optcally active compounds | SANYO CHEMICAL INDUSTRIES LTD. (JP) | 1990-09-05 | — | — | EP | disclosed |
| EP-0360622-A2 | Novel optically active benzene derivatives, process for producing the same and liquid-crystalline composition containing said derivatives as liquid-crystalline compound and light switching elements | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-03-28 | — | — | EP | disclosed |
| EP-0288297-A2 | Optically active benzene derivatives and process for preparation thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-10-26 | — | — | EP | disclosed |
| US-3933889-A | 4,5-Cis-didehydro-PGF1.sub.α analogs | THE UPJOHN COMPANY (US) | 1976-01-20 | — | — | US | disclosed |