SCHEMBL9429261

SCHEMBL9429261

[CH2]C(F)CCCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.48
TSHR P16473 1/20 0.44
THRB P10828 1/20 0.44
LMNA P02545 1/20 0.44
DNM1 Q05193 5/20 0.43
OPRM1 P35372 1/20 0.42
GPR84 Q9NQS5 3/20 0.39
FDPS P14324 3/20 0.39
SPHK1 Q9NYA1 1/20 0.39
FFAR1 O14842 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4317995 1.00
SCHEMBL9427945 1.00 MAPT (0.48) MAPTTSHRTHRBLMNADNM1
SCHEMBL9427804 1.00 MAPT (0.48) MAPTTSHRTHRBLMNADNM1
SCHEMBL9427876 1.00 MAPT (0.48) MAPTTSHRTHRBLMNADNM1
SCHEMBL7751087 1.00 MAPT (0.48) MAPTTSHRTHRBLMNADNM1
SCHEMBL5573758 1.00 MAPT (0.48) MAPTTSHRTHRBLMNADNM1
SCHEMBL42499 0.97
SCHEMBL9725075 0.97
SCHEMBL8082557 0.97
SCHEMBL477825 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5290478-A Nitrile containing naphthylene compound SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1994-03-01 US disclosed
EP-0385692-B1 OPTCALLY ACTIVE COMPOUNDS SANYO CHEMICAL INDUSTRIES LTD. (JP) 1993-10-06 EP disclosed
EP-0542381-A2 Optically active compounds SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1993-05-19 EP disclosed
EP-0518636-A1 Liquid crystal compounds and compositions SANYO CHEMICAL INDUSTRIES LTD. (JP) 1992-12-16 EP disclosed
EP-0517498-A1 Liquid crystal compounds and compositions SANYO CHEMICAL INDUSTRIES LTD. (JP) 1992-12-09 EP disclosed
US-5160662-A Improved response times SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1992-11-03 US disclosed
EP-0409634-A2 Liquid crystal compounds and optically active compounds SANYO CHEMICAL INDUSTRIES LTD. (JP) 1991-01-23 EP disclosed
EP-0385692-A2 Optcally active compounds SANYO CHEMICAL INDUSTRIES LTD. (JP) 1990-09-05 EP disclosed