Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5604826 | 0.82 | BRD4 (0.33) | PDCD1CD274ADRB2CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL27464627 | 0.82 | PDCD1 (0.33) | PDCD1CD274ADRB2CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL27477688 | 0.82 | PDCD1 (0.33) | PDCD1CD274ADRB2CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL27463818 | 0.82 | PDCD1 (0.33) | PDCD1CD274ADRB2CHRNB2CHRNA4 | |
| SCHEMBL5859122 | 0.81 | PDCD1 (0.34) | PDCD1CD274ADRB2CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL27546250 | 0.81 | PDCD1 (0.32) | PDCD1CD274ADRB2CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL27479364 | 0.81 | PDCD1 (0.32) | PDCD1CD274ADRB2CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL27478130 | 0.81 | PDCD1 (0.32) | PDCD1CD274ADRB2CHRNB2CHRNA4 | |
| SCHEMBL7644720 | 0.80 | PDCD1 (0.33) | PDCD1CD274ADRB2CHRNB2CHRNA4 | |
| SCHEMBL6649301 | 0.80 | PDCD1 (0.33) | PDCD1CD274ADRB2CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090012238-A1 | RESIN COMPOSITION, TRANSPARENT FILM OR SHEET HAVING ELASTICITY RECOVERING PROPERTY, AND WRAP FILM | PRIME POLYMER CO., LTD (JP) | 2009-01-08 | — | — | US | disclosed |