SCHEMBL4249987

SCHEMBL4249987

C[SiH](O)CCCO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17675765 0.79 TSHR (0.41)
SCHEMBL5065421 0.76
SCHEMBL26187834 0.76 ALDH1A1 (0.39)
Fluoride SCHEMBL28146149 0.73
SCHEMBL1827817 0.73
SCHEMBL4249986 0.71
SCHEMBL18088824 0.71
SCHEMBL28330417 0.71
SCHEMBL7764730 0.71
SCHEMBL8623522 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180100039-A1 TRI-BLOCK PREPOLYMERS AND THEIR USE IN SILICONE HYDROGELS JOHNSON & JOHNSON VISION CARE, INC. 2018-04-12 US disclosed
US-20180011223-A1 SILICONE HYDROGELS COMPRISING N-ALKYL METHACRYLAMIDES AND CONTACT LENSES MADE THEREOF JOHNSON & JOHNSON VISION CARE, INC. 2018-01-11 US disclosed
US-20160313571-A1 INCREASED STIFFNESS CENTER OPTIC IN SOFT CONTACT LENSES FOR ASTIGMATISM CORRECTION JOHNSON & JOHNSON VISION CARE, INC. 2016-10-27 US disclosed
US-7902392-B2 Method for the production of organosilicon compounds comprising carboxy radicals WACKER CHEMIE AG (DE) 2011-03-08 US disclosed
US-20090221842-A1 METHOD FOR THE PRODUCTION OF ORGANOSILICON COMPOUNDS COMPRISING CARBOXY RADICALS WACKER CHEMIE AG (DE) 2009-09-03 US disclosed
US-7074950-B2 Process for preparing organosilicon compounds WACKER-CHEMIE GMBH (DE) 2006-07-11 US disclosed
US-20050137412-A1 Process for preparing organosilicon compounds WACKER-CHEMIE GMBH (DE) 2005-06-23 US disclosed
EP-1082327-A4 PERFLUORINATED ORGANO SUBSTITUTED CYCLOSILOXANES AND COPOLYMERS PREPARED FROM THESE CYCLOSILOXANES CLARIANT LSM ITALIA SPA (US) 2003-04-16 EP disclosed
EP-1082327-A1 PERFLUORINATED ORGANO SUBSTITUTED CYCLOSILOXANES AND COPOLYMERS PREPARED FROM THESE CYCLOSILOXANES Archimica (Florida), Inc. (US) 2001-03-14 EP disclosed
WO-1999062916-A1 PERFLUORINATED ORGANO SUBSTITUTED CYCLOSILOXANES AND COPOLYMERS PREPARED FROM THESE CYCLOSILOXANES ARCHIMICA (FLORIDA) INC. (US) 1999-12-09 WO disclosed
US-5914420-A UNSTRAINED POLYMERIZABLE CYCLOSILOXANES HAVING A SUBSTITUENT THAT CONTAINS A PERFLUORINATED ORGANIC MOIETY PCR, INC. (US) 1999-06-22 US disclosed
EP-0907685-A1 USE OF PLATINUM COMPLEXES PARTICULARLY AS HOMOGENEOUS AND HEAT ACTIVABLE CATALYSTS FOR HYDROSILYLATION RHODIA CHIMIE (FR) 1999-04-14 EP disclosed
US-5892086-A Perfluorinated ether organo substituted cyclosiloxanes and copolymers prepared from these cyclosiloxanes PCR, INC. (US) 1999-04-06 US disclosed
US-5795947-A RELEASE PAPER COATINGS RHONE-POULENC CHIMIE (FR) 1998-08-18 US disclosed
WO-1998000463-A1 USE OF PLATINUM COMPLEXES PARTICULARLY AS HOMOGENEOUS AND HEAT ACTIVABLE CATALYSTS FOR HYDROSILYLATION RHODIA CHIMIE (FR) 1998-01-08 WO disclosed
EP-0750624-A1 PLATINUM COMPLEXES AND LIGHT-ACTIVATABLE HYDROSILYLATION CATALYSTS CONTAINING SAME RHONE-POULENC CHIMIE (FR) 1997-01-02 EP disclosed
EP-0750623-A1 PLATINUM COMPLEXES AND LIGHT-ACTIVATABLE HYDROSILYLATION CATALYSTS CONTAINING SAME RHONE-POULENC CHIMIE (FR) 1997-01-02 EP disclosed
WO-1995025735-A1 PLATINUM COMPLEXES AND LIGHT-ACTIVATABLE HYDROSILYLATION CATALYSTS CONTAINING SAME RHONE POULENC CHIMIE (FR) 1995-09-28 WO disclosed
WO-1995025734-A1 PLATINUM COMPLEXES AND LIGHT-ACTIVATABLE HYDROSILYLATION CATALYSTS CONTAINING SAME RHONE POULENC CHIMIE (FR) 1995-09-28 WO disclosed
EP-0632085-A1 Silicone polymers having olefinic functional groups, process for their preparation, and curable compositions comprising them RHONE-POULENC CHIMIE (FR) 1995-01-04 EP disclosed