Indazole Carboxamide

Indazole Carboxamide

SCHEMBL42505

NC(=O)n1ncc2ccccc21

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A12 Q96S37 1/20 0.53
ELANE P08246 1/20 0.53
ASAH1 Q13510 2/20 0.49
TFPI2 P48307 1/20 0.49
KMO O15229 1/20 0.47
PKM P14618 1/20 0.44
CHEK1 O14757 1/20 0.44
AURKA O14965 1/20 0.44
DAPK3 O43293 1/20 0.44
CSNK1A1 P48729 1/20 0.44
GSK3A P49840 1/20 0.44
LIMK1 P53667 1/20 0.44
IKBKE Q14164 1/20 0.44
MAPK14 Q16539 1/20 0.44
TAOK1 Q7L7X3 1/20 0.44
CLK4 Q9HAZ1 1/20 0.44
DYRK1B Q9Y463 1/20 0.44
RECQL P46063 2/20 0.41
DAO P14920 2/20 0.38
POLB P06746 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indazole Carboxamide SCHEMBL15638369 0.98 SLC22A12 (0.51) SLC22A12ELANEASAH1TFPI2KMO
SCHEMBL4423022 0.84 SLC22A12 (0.55) SLC22A12ELANEASAH1TFPI2KMO
SCHEMBL260982 0.82 SLC22A12 (0.54) SLC22A12ELANEASAH1TFPI2KMO
SCHEMBL2460851 0.82 SLC22A12 (0.48) SLC22A12ELANEASAH1TFPI2KMO
SCHEMBL1087434 0.81 CHEK1 (0.60) SLC22A12ELANEASAH1TFPI2KMO
SCHEMBL5745198 0.81 SLC22A12 (0.45) SLC22A12ELANEASAH1TFPI2KMO
Hydrochloric Acid SCHEMBL30581596 0.81 SLC22A12 (0.53) SLC22A12ELANEASAH1TFPI2KMO
SCHEMBL9123802 0.81 ELANE (0.49) SLC22A12ELANEASAH1TFPI2KMO
SCHEMBL2025416 0.81 SLC22A12 (0.56) SLC22A12ELANEASAH1TFPI2KMO
SCHEMBL15349270 0.80 ASAH1 (0.56) SLC22A12ELANEASAH1TFPI2KMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 711 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121586714-A Connected bicyclic compounds for control and combating invertebrate pests FMC公司 2026-02-27 CN claimed
CN-119907626-A Compositions having pesticidal utility and methods related thereto 科迪华农业科技有限责任公司 2025-04-29 CN claimed
CN-119907790-A Pyrazole amide insecticidal agents FMC公司 2025-04-29 CN claimed
CN-118922081-A Insect, acarina and nematode pest control 先正达农作物保护股份公司 2024-11-08 CN claimed
CN-118914543-A Detection system for synthesizing cannabinoid and application thereof 中国药科大学 2024-11-08 CN claimed
CN-117998986-A Insect, acarina and nematode pest control 先正达农作物保护股份公司 2024-05-07 CN claimed
CN-114605329-B Substituted indazole carboxamides or substituted azaindazole carboxamides FLT3 inhibitors and uses thereof 河南中医药大学 2024-01-26 CN claimed
CN-112300074-B Indazole carboxamide compound and preparation method and application thereof 北京盈科瑞创新药物研究有限公司 2023-12-29 CN claimed
CN-116916751-A Insect and acarina pest control 先正达农作物保护股份公司 2023-10-20 CN claimed
EP-2903978-B1 GDF-8 INHIBITORS RIGEL PHARMACEUTICALS INC (US) 2022-12-07 EP claimed
WO-2004074275-A1 INDAZOLAMIDES WITH ANALGESIC ACTIVITY AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) 2004-09-02 WO claimed
EP-0975623-B1 INDAZOLE AMIDE COMPOUNDS AS SEROTONINERGIC AGENTS ACRAF (IT) 2002-06-19 EP claimed
WO-2002036113-A1 COMPOSITION COMPRISING: SEROTONIN RECEPTOR ANTAGONISTS (5HT-2, 5HT-3) AND AGONIST (5HT-4) RESPIRATORIUS AB (SE) 2002-05-10 WO claimed
WO-2001095902-A9 A COMPOSITION COMPRISING A COMBINATION OF RECEPTOR AGONISTS AND ANTAGONISTS 2002-04-25 WO claimed
WO-2001095902-A1 A COMPOSITION COMPRISING A COMBINATION OF RECEPTOR AGONISTS AND ANTAGONISTS RESPIRATORIUS AB (SE) 2001-12-20 WO claimed
US-6197769-B1 SEROTONINE RECEPTORS ANTAGONIST; GASTROINTESTINAL DISORDERS, ANTIARRHYTHMIA AGENTS; INCONTINENCE AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) 2001-03-06 US claimed
CN-1252798-A Indazole amide compounds as 5-serotoninergic agents ANGELINI RICERCHE SPA (IT) 2000-05-10 CN claimed
EP-0975623-A2 INDAZOLE AMIDE COMPOUNDS AS SEROTONINERGIC AGENTS AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A. (IT) 2000-02-02 EP claimed
WO-1998046589-B1 INDAZOLE AMIDE COMPOUNDS AS SEROTONINERGIC AGENTS 1999-03-04 WO claimed
WO-1998046589-A2 INDAZOLE AMIDE COMPOUNDS AS SEROTONINERGIC AGENTS AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) 1998-10-22 WO claimed