Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.55 |
| ▸ | ELANE | P08246 | 1/20 | 0.55 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.51 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.51 |
| ▸ | KMO | O15229 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL260982 | 0.86 | SLC22A12 (0.54) | SLC22A12ELANEASAH1TFPI2KMO | |
| SCHEMBL1087434 | 0.84 | CHEK1 (0.60) | SLC22A12ELANEASAH1TFPI2KMO | |
| SCHEMBL2025416 | 0.84 | SLC22A12 (0.56) | SLC22A12ELANEASAH1TFPI2KMO | |
| Indazole Carboxamide SCHEMBL42505 | 0.84 | SLC22A12 (0.53) | SLC22A12ELANEASAH1TFPI2KMO | |
| Hydrochloric Acid SCHEMBL30581596 | 0.84 | SLC22A12 (0.53) | SLC22A12ELANEASAH1TFPI2KMO | |
| SCHEMBL8544774 | 0.83 | TFPI2 (0.46) | SLC22A12ELANEASAH1TFPI2POLB | |
| Indazole Carboxamide SCHEMBL15638369 | 0.82 | SLC22A12 (0.51) | SLC22A12ELANEASAH1TFPI2KMO | |
| SCHEMBL496975 | 0.81 | ELANE (0.70) | SLC22A12ELANEASAH1TFPI2KMO | |
| SCHEMBL27987640 | 0.81 | ALDH1A1 (0.51) | SLC22A12ELANEASAH1TFPI2CYP1A2 | |
| SCHEMBL2034393 | 0.81 | HTT (0.51) | SLC22A12ELANEASAH1TFPI2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107969127-A | APOA-1 FUSION POLYPEPTIDES AND RELATED COMPOSITIONS AND METHODS | 赛瑞品股份有限公司 | 2018-04-27 | — | — | CN | disclosed |
| US-7622594-B2 | Glucocortioid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |
| EP-1893588-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2008-03-05 | — | — | EP | disclosed |
| US-20070060633-A1 | Glucocortioid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2007-03-15 | — | — | US | disclosed |
| WO-2006135826-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-12-21 | — | — | WO | disclosed |
| US-6372778-B1 | AMINE HYDROXYALKYL SULFONAMIDE AS ENZYME INHIBITORS | VERTEX PHARMACEUTICALS, INCORPORATED | 2002-04-16 | — | — | US | disclosed |
| US-4443246-A | Herbicidal pyridyl-ethoxy-phenyl urea derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-04-17 | — | — | US | disclosed |
| EP-0067718-A1 | Urea derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-12-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060633-A1 | Glucocortioid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | NR3C1, MC2R, NR3C2 | SLC22A12 820/4885ELANE 836/4885ASAH1 1090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.