Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 8/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | HTT | P42858 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | TYR | P14679 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27385678 | 0.99 | HSD17B3 (0.52) | HSD17B3GAAALDH1A1ERAP1POLB | |
| SCHEMBL4527127 | 0.99 | HSD17B3 (0.55) | HSD17B3GAAALDH1A1ERAP1POLB | |
| SCHEMBL27844746 | 0.94 | GAA (0.58) | HSD17B3GAAALDH1A1ERAP1POLB | |
| SCHEMBL15082511 | 0.88 | HSD17B3 (0.59) | HSD17B3GAAALDH1A1ERAP1POLB | |
| SCHEMBL30405545 | 0.84 | HSD17B3 (0.65) | HSD17B3GAAALDH1A1ERAP1POLB | |
| SCHEMBL220708 | 0.84 | HSD17B3 (0.65) | HSD17B3GAAALDH1A1ERAP1POLB | |
| SCHEMBL27380273 | 0.83 | MAOA (0.56) | HSD17B3GAAALDH1A1ERAP1MEN1 | |
| SCHEMBL11878333 | 0.82 | SRC (0.58) | GAAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL28535264 | 0.81 | MAOB (0.59) | GAAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL21385208 | 0.81 | MAOB (0.59) | GAAALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118129-A2 | ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES | Life Technologies Corporation (US) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008106660-A2 | ISOLATED PHOSPHOLIPID-PROTEIN PARTICLES | INVITROGEN CORPORATION (US) | 2008-09-04 | — | — | WO | disclosed |