SCHEMBL4251709

SCHEMBL4251709

Cc1nc(-c2ccc(CF)cc2)sc1COc1ccc(C2COC(C)(C(=O)O)OC2)cc1

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 14/20 0.52
FFAR1 O14842 14/20 0.52
PPARA Q07869 6/20 0.51
PPARG P37231 6/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4251716 1.00 PPARD (0.52) PPARDFFAR1PPARAPPARG
SCHEMBL4243257 0.90 PPARD (0.63) PPARDFFAR1PPARAPPARG
SCHEMBL4243261 0.90 PPARD (0.63) PPARDFFAR1PPARAPPARG
SCHEMBL4247493 0.90 PPARD (0.63) PPARDFFAR1PPARAPPARG
SCHEMBL4243427 0.81 PPARD (0.59) PPARDFFAR1PPARAPPARG
SCHEMBL4250723 0.81 PPARD (0.59) PPARDFFAR1PPARAPPARG
SCHEMBL4254697 0.81 PPARD (0.66) PPARDFFAR1PPARAPPARG
SCHEMBL4246297 0.81 PPARD (0.66) PPARDFFAR1PPARAPPARG
SCHEMBL4246301 0.81 PPARD (0.66) PPARDFFAR1PPARAPPARG
SCHEMBL4251717 0.74 PPARD (0.49) PPARDFFAR1PPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090012069-A1 Novel Antidiabetic Compounds CADILA HEALTHCARE LIMITED (IN) 2009-01-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090012069-A1 Novel Antidiabetic Compounds GPR119, SLC5A1, SLC5A2 PPARD 54/4885FFAR1 405/4885PPARA 145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.