Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4245572 | 0.87 | F10 (0.35) | F10OPRM1 | |
| SCHEMBL4243981 | 0.86 | F10 (0.38) | F10OPRM1 | |
| SCHEMBL4250023 | 0.85 | F10 (0.42) | F10OPRM1 | |
| SCHEMBL3380174 | 0.85 | F10 (0.43) | F10OPRM1 | |
| SCHEMBL4245786 | 0.83 | F10 (0.41) | F10OPRM1 | |
| SCHEMBL4247278 | 0.83 | F10 (0.35) | F10OPRM1 | |
| SCHEMBL12889135 | 0.82 | F10 (0.43) | F10 | |
| SCHEMBL3380134 | 0.82 | PREP (0.35) | F10OPRM1 | |
| SCHEMBL8225156 | 0.81 | F10 (0.38) | F10 | |
| SCHEMBL4244644 | 0.81 | F10 (0.35) | F10OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029589-A1 | DIHYDRO-PYRROLOPYRIDINE-, DIHYDRO-PYRROLOPYRIDAZINE- AND DIHYDRO-PYRROLOPYRIMIDINE-DERIVATIVES AND USE THEREOF | Bayer HealthCare AG (DE) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007137793-A1 | DIHYDRO-PYRROLOPYRIDINE-, DIHYDRO-PYRROLOPYRIDAZINE- AND DIHYDRO-PYRROLOPYRIMIDINE-DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-12-06 | — | — | WO | disclosed |