SCHEMBL4252001

SCHEMBL4252001

CCCCCCCCOp1oc2c(C(C)(C)C)cc(C(C)(C)C)cc2c2cc(C(C)(C)C)cc(C(C)(C)C)c2o1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RXRA P19793 2/20 0.34
RXRB P28702 1/20 0.34
RXRG P48443 1/20 0.34
NR5A2 O00482 1/20 0.33
NR5A1 Q13285 1/20 0.33
GHSR Q92847 1/20 0.32
THRA P10827 1/20 0.31
THRB P10828 1/20 0.31
PPARG P37231 1/20 0.30
FAAH O00519 1/20 0.30
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7145505 1.00 RXRA (0.34) RXRARXRBRXRGNR5A2NR5A1
SCHEMBL14393076 0.93 RXRA (0.33) RXRARXRBRXRGNR5A2NR5A1
SCHEMBL13290054 0.89 RARG (0.31) RXRANR5A2NR5A1PPARG
SCHEMBL17264263 0.88 HTR1D (0.30)
SCHEMBL39578 0.86
SCHEMBL13246061 0.83 CYP1A2 (0.31)
SCHEMBL86121 0.82 HTR1D (0.37)
SCHEMBL31194410 0.82 HTR1D (0.37)
SCHEMBL250134 0.81
SCHEMBL3677817 0.80 HPGD (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009092494-A1 UV-ABSORBENT COORDINATION POLYMER BASF SE (DE) 2009-07-30 WO disclosed