Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 6/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5498852 | 0.92 | P2RY12 (0.43) | P2RY12PDPK1HTTMCHR1 | |
| Hydrochloric Acid SCHEMBL4811911 | 0.92 | P2RY12 (0.42) | P2RY12PDPK1HTTMCHR1 | |
| SCHEMBL4251739 | 0.87 | ALOX15 (0.48) | P2RY12 | |
| SCHEMBL4254095 | 0.86 | MAPT (0.46) | P2RY12HTTDRD2DRD3HRH3 | |
| Dimethylamine SCHEMBL5498858 | 0.79 | P2RY12 (0.51) | P2RY12 | |
| SCHEMBL4817283 | 0.79 | ALOX15 (0.51) | P2RY12 | |
| Dimethylamine SCHEMBL4811919 | 0.78 | P2RY12 (0.50) | P2RY12 | |
| SCHEMBL443671 | 0.78 | HDAC6 (0.51) | P2RY12HTTDRD2DRD3HRH3 | |
| SCHEMBL5498843 | 0.77 | HDAC1 (0.39) | P2RY12MAOB | |
| SCHEMBL4250108 | 0.77 | PDPK1 (0.39) | PDPK1HTTDRD2DRD3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023798-A1 | THIOHYDROXAMATES AS INHIBITORS OF HISTONE DEACETYLASE | PHARMACYCLICS, INC. (US) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023798-A1 | THIOHYDROXAMATES AS INHIBITORS OF HISTONE DEACETYLASE | HDAC1, HDAC8, HDAC3 | P2RY12 4605/4885PDPK1 2534/4885HTT 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.