Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 9/20 | 0.44 |
| ▸ | GSK3A | P49840 | 3/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.44 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3004295 | 0.90 | LMNA (0.56) | LMNAPIM1GSK3APIM3GSK3B | |
| SCHEMBL12673659 | 0.86 | LMNA (0.55) | LMNAPIM1GSK3APIM3GSK3B | |
| SCHEMBL12673660 | 0.84 | LMNA (0.52) | LMNAPIM1GSK3APIM3GSK3B | |
| SCHEMBL12665506 | 0.83 | LMNA (0.51) | LMNAPIM1GSK3APIM3GSK3B | |
| SCHEMBL10976342 | 0.82 | PIM1 (0.63) | LMNAPIM1GSK3APIM3GSK3B | |
| SCHEMBL12665505 | 0.81 | LMNA (0.49) | LMNAPIM1GSK3APIM3GSK3B | |
| SCHEMBL9568381 | 0.81 | LMNA (0.49) | LMNAPIM1GSK3APIM3GSK3B | |
| SCHEMBL9568396 | 0.81 | LMNA (0.49) | LMNAPIM1GSK3APIM3GSK3B | |
| SCHEMBL9522209 | 0.81 | LMNA (0.67) | LMNAPIM1GSK3APIM3GSK3B | |
| SCHEMBL9523600 | 0.80 | LMNA (0.50) | LMNAPIM1GSK3APIM3GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009093268-A1 | PROCESS FOR THE PREPARATION OF HIGHLY PURE PRULIFLOXACIN | IND-SWIFT LABORATORIES LIMITED (IN) | 2009-07-30 | — | — | WO | disclosed |