SCHEMBL4252233

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL445670	0.91	HDAC3 (0.55)	HPGDTSHRSMN1; SMN2HDAC3HDAC1
	SCHEMBL4258436	0.89	HPGD (0.51)	HPGDTSHRSMN1; SMN2HDAC3HDAC1
	SCHEMBL4248678	0.87	HPGD (0.52)	HPGDTSHRSMN1; SMN2HDAC3HDAC1
	SCHEMBL4248226	0.85	HDAC1 (0.59)	HPGDTSHRSMN1; SMN2HDAC1HDAC2
	SCHEMBL445770	0.84	HDAC3 (0.54)	HPGDTSHRSMN1; SMN2HDAC3HDAC1
	SCHEMBL4253910	0.84	NMT2 (0.48)	HPGDTSHRSMN1; SMN2HDAC3HDAC1
	SCHEMBL4255646	0.83	HTT (0.43)	HPGDTSHRSMN1; SMN2HDAC1HDAC2
	SCHEMBL4247735	0.82	HPGD (0.73)	HPGDTSHRSMN1; SMN2HDAC3HDAC1
	SCHEMBL3665161	0.82	HDAC2 (0.53)	HPGDTSHRSMN1; SMN2HDAC3HDAC1
	SCHEMBL4247798	0.82	HDAC3 (0.60)	HPGDTSHRSMN1; SMN2HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.