Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4064993 | 0.87 | — | — | |
| SCHEMBL4067780 | 0.83 | CYP8B1 (0.38) | KCNH2 | |
| SCHEMBL5520098 | 0.75 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL4070188 | 0.74 | HTR1A (0.42) | — | |
| SCHEMBL14610739 | 0.74 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL14610698 | 0.73 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL5523706 | 0.73 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL14610699 | 0.73 | KCNH2 (0.46) | KCNH2 | |
| SCHEMBL3273831 | 0.72 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL3273828 | 0.72 | KCNH2 (0.44) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1605938-B1 | Antibacterial derivatives of napthydrin and quinoline | GLAXO GROUP LTD (GB) | 2009-02-11 | — | — | EP | disclosed |