⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587699 | 0.94 | — | — | |
| SCHEMBL6586970 | 0.92 | KMT2A (0.32) | — | |
| SCHEMBL910899 | 0.81 | — | — | |
| SCHEMBL6589728 | 0.81 | CYP2C9 (0.33) | — | |
| SCHEMBL7075561 | 0.79 | CYP2C9 (0.32) | — | |
| SCHEMBL3296363 | 0.77 | — | — | |
| SCHEMBL22878856 | 0.77 | — | — | |
| SCHEMBL132918 | 0.77 | — | — | |
| SCHEMBL601777 | 0.77 | — | — | |
| SCHEMBL599393 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4347597-A1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2024-04-10 | — | — | EP | claimed |
| CN-117377674-A | Pyrazolo [1,5-a ] pyrimidine compounds for the treatment of dermatological disorders | 大塚制药株式会社 | 2024-01-09 | — | — | CN | claimed |
| WO-2022255408-A1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-12-08 | — | — | WO | claimed |
| US-9580615-B2 | Phase change inks comprising inorganic nucleating agents | XEROX CORPORATION (US) | 2017-02-28 | — | — | US | claimed |
| US-9528015-B2 | Phase change ink compositions comprising crystalline diurethanes and derivatives thereof | XEROX CORPORATION (US) | 2016-12-27 | — | — | US | claimed |
| US-8778069-B2 | Phase change inks containing oligomeric rosin esters | XEROX CORPORATION (US) | 2014-07-15 | — | — | US | claimed |
| US-20140139599-A1 | PHASE CHANGE INKS COMPRISING INORGANIC NUCLEATING AGENTS | XEROX CORPORATION (US) | 2014-05-22 | — | — | US | claimed |
| US-20140139591-A1 | INK COMPOSITIONS INCORPORATING ESTER RESINS | XEROX CORPORATION (US) | 2014-05-22 | — | — | US | claimed |
| US-20140137767-A1 | Phase Change Inks Containing Oligomeric Rosin Esters | XEROX CORPORATION (US) | 2014-05-22 | — | — | US | claimed |
| US-20130284056-A1 | PHASE CHANGE INK COMPOSITIONS COMPRISING CRYSTALLINE DIURETHANES AND DERIVATIVES THEREOF | XEROX CORPORATION (US) | 2013-10-31 | — | — | US | claimed |
| US-5118702-A | FUNGICIDAL AND MICROBICIDAL SUBSTITUTED 1-AMINOMETHYL-3-ARYL-4-CYANO-PYRROLES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | claimed |
| EP-0435043-A1 | Substituted 1-aminomethyl-3-aryl-4-cyano-pyrroles | BAYER AG (DE) | 1991-07-03 | — | — | EP | claimed |
| EP-4347597-A1 | PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2024-04-10 | — | — | EP | disclosed |
| CN-117377674-A | Pyrazolo [1,5-a ] pyrimidine compounds for the treatment of dermatological disorders | 大塚制药株式会社 | 2024-01-09 | — | — | CN | disclosed |
| CN-112980543-B | High viscosity index comb polymer viscosity modifiers and methods of using the same to alter lubricant viscosity | 英菲诺姆国际有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-112980549-B | High viscosity index comb polymer viscosity modifiers and methods of using the same to alter lubricant viscosity | 英菲诺姆国际有限公司 | 2023-12-15 | — | — | CN | disclosed |
| EP-0060640-A1 | 5,6,7-Trinor-4,8-inter-m-phenylene PGI derivatives and pharmaceutical compositions containing them | TORAY INDUSTRIES, INC. (JP) | 1982-09-22 | — | — | EP | disclosed |
| US-4301164-A | FOR USE AS ANTIULCER AGENTS, HYPOTENSIVE AGENTS, ANTITHROMBOSIC AGENTS | TORAY INDUSTRIES, INC. (JP) | 1981-11-17 | — | — | US | disclosed |
| EP-0024943-A1 | 5,6,7-Trinor-4,8-inter-m-phenylene PGI2 derivatives and pharmaceutical compositions containing them | TORAY INDUSTRIES, INC. (JP) | 1981-03-11 | — | — | EP | disclosed |
| US-4187251-A | DEODORIZING, ALKYLCYCLOHEXYL ALKYL KETONES | SCHLEPPNIK ALFRED A | 1980-02-05 | — | — | US | disclosed |