SCHEMBL4252638

SCHEMBL4252638

CCC(c1cc2c(Cl)c(C)nn2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(OC)cc1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4252643 1.00 KIF11 (0.56) KIF11
SCHEMBL4251600 0.92 KIF11 (0.65) KIF11
SCHEMBL4251604 0.92 KIF11 (0.65) KIF11
Hydrochloric Acid SCHEMBL4250319 0.92 KIF11 (0.65) KIF11
Hydrochloric Acid SCHEMBL4249019 0.92 KIF11 (0.65) KIF11
Hydrochloric Acid SCHEMBL4250132 0.92 KIF11 (0.65) KIF11
SCHEMBL4250107 0.90 KIF11 (0.51) KIF11
SCHEMBL4250105 0.90 KIF11 (0.51) KIF11
SCHEMBL4244626 0.87 KIF11 (0.58) KIF11
SCHEMBL4244628 0.87 KIF11 (0.58) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2035426-A1 PYRAZOLOPYRIMIDONES 4SC AG (DE) 2009-03-18 EP disclosed
WO-2007144384-A1 PYRAZOLOPYRIMIDONES 4SC AG (DE) 2007-12-21 WO disclosed