Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | ESRRG | P62508 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3442788 | 0.80 | KDM1A (0.39) | KDM1AALDH1A1ALOX15ESR1ESR2 | |
| SCHEMBL3442786 | 0.80 | KDM1A (0.39) | KDM1AALDH1A1ALOX15ESR1ESR2 | |
| SCHEMBL10587987 | 0.79 | TSHR (0.40) | ALDH1A1MAPTKMT2ACES1CES2 | |
| SCHEMBL10587991 | 0.79 | TSHR (0.40) | ALDH1A1MAPTKMT2ACES1CES2 | |
| SCHEMBL2989490 | 0.78 | KDM1A (0.38) | KDM1AALDH1A1ALOX15ESR1ESR2 | |
| SCHEMBL713860 | 0.77 | KDM1A (0.42) | KDM1AALDH1A1ESR1MAPK1KMT2A | |
| SCHEMBL7551195 | 0.75 | KDM1A (0.41) | KDM1AALDH1A1ESR1MAPK1MAPT | |
| SCHEMBL28792582 | 0.75 | KDM1A (0.41) | KDM1AALDH1A1ESR1MAPK1CES1 | |
| SCHEMBL9814341 | 0.75 | KDM1A (0.41) | KDM1AALDH1A1ESR1MAPK1MAPT | |
| SCHEMBL10631105 | 0.72 | TAAR1 (0.40) | KDM1AALDH1A1ALOX15ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482419-B2 | Silsesquioxane resin wax | DOW CORNING CORPORATION (US) | 2009-01-27 | — | — | US | disclosed |
| EP-1751215-B1 | SILSESQUIOXANE RESIN WAX | DOW CORNING (US) | 2007-08-29 | — | — | EP | disclosed |
| US-20070149703-A1 | Silsesquioxane resin wax | DOW CORNING CORPORATION (US) | 2007-06-28 | — | — | US | disclosed |