SCHEMBL4252899

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4245726	0.92	TLR7 (0.41)	TLR7TLR8NUDT1ACSS2
	SCHEMBL4245720	0.92	TLR7 (0.41)	TLR7TLR8NUDT1ACSS2
	SCHEMBL4247825	0.86	TLR7 (0.41)	TLR7TLR8CA12CA1CA2
	SCHEMBL4239964	0.85	TLR7 (0.46)	TLR7TLR8CA12CA1CA2
	SCHEMBL4239486	0.84	TLR8 (0.41)	TLR7TLR8CA12CA1CA2
	SCHEMBL4246941	0.80	DYRK1A (0.43)	TLR7CA12CA1CA2CA9
	SCHEMBL5618020	0.80	TLR7 (0.62)	TLR7TLR8NUDT1
	SCHEMBL5113144	0.80	TLR7 (0.48)	TLR7TLR8NUDT1
	SCHEMBL5364581	0.79	TLR7 (0.47)	TLR7TLR8NUDT1
	SCHEMBL4241950	0.79	TLR7 (0.39)	TLR7TLR8DYRK1AACSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.