Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4257359 | 0.94 | AOC3 (0.45) | AOC3NPC1PKMRAB9AITGB3 | |
| SCHEMBL4254816 | 0.86 | NPC1 (0.43) | AOC3NPC1PKMRAB9AITGB3 | |
| SCHEMBL4260430 | 0.86 | APP (0.43) | AOC3NPC1PKMRAB9AITGB3 | |
| SCHEMBL4251106 | 0.80 | NPC1 (0.43) | AOC3NPC1PKMRAB9A | |
| SCHEMBL4251146 | 0.80 | APP (0.45) | AOC3NPC1PKMRAB9AMAOA | |
| SCHEMBL4250029 | 0.79 | NPC1 (0.63) | NPC1PKMRAB9A | |
| SCHEMBL4250573 | 0.79 | ALDH1A1 (0.50) | NPC1RAB9A | |
| SCHEMBL10086453 | 0.73 | TP53 (0.49) | AOC3NPC1PKMRAB9A | |
| SCHEMBL4255711 | 0.72 | NPC1 (0.51) | NPC1RAB9A | |
| SCHEMBL4255714 | 0.72 | NPC1 (0.46) | NPC1PKMRAB9AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009054653-A2 | ISOINDOLONES WITH HIGH BINDING AFFINITY TO BETA-AMYLOID AGGREGATES AND FIBRILS, AND ITS USE AND PREPARATION METHOD | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-04-30 | — | — | WO | disclosed |