Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL734580 | 0.82 | HTR1B (0.48) | SIGMAR1L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL29657743 | 0.79 | SIGMAR1 (0.54) | SIGMAR1L3MBTL1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL517207 | 0.79 | SIGMAR1 (0.54) | SIGMAR1L3MBTL1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL14461587 | 0.79 | SIGMAR1 (0.54) | SIGMAR1L3MBTL1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL28274542 | 0.79 | HTR1B (0.42) | SIGMAR1ALDH1A1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL28274536 | 0.79 | HTR1B (0.42) | SIGMAR1ALDH1A1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL1593235 | 0.78 | SIGMAR1 (0.43) | SIGMAR1ALDH1A1KMT2ACYP1A2CYP2D6 | |
| Bromide SCHEMBL7412701 | 0.78 | SIGMAR1 (0.53) | SIGMAR1L3MBTL1ALDH1A1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL4747710 | 0.78 | SIGMAR1 (0.53) | SIGMAR1L3MBTL1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL29862183 | 0.78 | SIGMAR1 (0.57) | SIGMAR1L3MBTL1ALDH1A1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773348-A4 | TETRAPEPTIDE ANALOGS | IDUN PHARMACEUTICALS INC (US) | 2009-05-20 | — | — | EP | disclosed |
| EP-1773348-A2 | TETRAPEPTIDE ANALOGS | Idun Pharmaceuticals, Inc. (US) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006017295-A2 | TETRAPEPTIDE ANALOGS | IDUN PHARMACEUTICALS, INC. (US) | 2006-02-16 | — | — | WO | disclosed |
| US-4081596-A | DIURETIC, SALURETIC, ANTIHYPERTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-28 | — | — | US | disclosed |
| US-4005215-A | DIURETIC | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-25 | — | — | US | disclosed |
| US-3978077-A | DIURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (GB) | 1976-08-31 | — | — | US | disclosed |
| US-3957814-A | DIURETICS, SALURETICS, HYPOTENSIVE AGENTS, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |